ArticleGenetics, selection, evolution : GSE2010
Epistatic QTL pairs associated with meat quality and carcass composition traits in a porcine Duroc × Pietrain population.
Article in Genetics, selection, evolution : GSE, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 23 citations in OpenAlex.
- Genomic dissection of maternal, additive and non-additive genetic effects for growth and carcass traits in Nile tilapia.Genetics, selection, evolution : GSE · 2020Article
- Genomic Prediction of Additive and Dominant Effects on Wool and Blood Traits in Alpine Merino Sheep.Frontiers in veterinary science · 2020Article
- Genome-Wide SNP Linkage Mapping and QTL Analysis for Fiber Quality and Yield Traits in the Upland Cotton Recombinant Inbred Lines Population.Frontiers in plant science · 2016Article
- Fine mapping and single nucleotide polymorphism effects estimation on pig chromosomes 1, 4, 7, 8, 17 and X.Genetics and molecular biology · 2013Article
- A genetical genomics approach reveals new candidates and confirms known candidate genes for drip loss in a porcine resource population.Mammalian genome : official journal of the International Mammalian Genome Society · 2013Article
- Genetic components and major QTL confer resistance to bean pyralid (Lamprosema indicata Fabricius) under multiple environments in four RIL populations of soybean.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
- Article
- Comparison of analyses of the QTLMAS XIV common dataset. II: QTL analysis.BMC proceedings · 2011Article
- QTLMAS 2010: simulated dataset.BMC proceedings · 2011Article
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Authors and funding
9 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQuantitative trait loci (QTL) analyses in pig have revealed numerous individual QTL affecting growth, carcass composition, reproduction and meat quality, indicating a complex genetic architecture. In general, statistical QTL models consider only additive and dominance effects and identification of epistatic effects in livestock is not yet widespread. The aim of this study was to identify and characterize epistatic effects between common and novel QTL regions for carcass composition and meat quality traits in pig.
methodsFive hundred and eighty five F₂ pigs from a Duroc × Pietrain resource population were genotyped using 131 genetic markers (microsatellites and SNP) spread over the 18 pig autosomes. Phenotypic information for 26 carcass composition and meat quality traits was available for all F₂ animals. Linkage analysis was performed in a two-step procedure using a maximum likelihood approach implemented in the QxPak program.
resultsA number of interacting QTL was observed for different traits, leading to the identification of a variety of networks among chromosomal regions throughout the porcine genome. We distinguished 17 epistatic QTL pairs for carcass composition and 39 for meat quality traits. These interacting QTL pairs explained up to 8% of the phenotypic variance.
conclusionsOur findings demonstrate the significance of epistasis in pigs. We have revealed evidence for epistatic relationships between different chromosomal regions, confirmed known QTL loci and connected regions reported in other studies. Considering interactions between loci allowed us to identify several novel QTL and trait-specific relationships of loci within and across chromosomes.
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