Trial reportSurgical endoscopy2011
Do dietary spices impair the patient-reported outcomes for stapled hemorrhoidopexy? A randomized controlled study.
Trial report in Surgical endoscopy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Biomolecular inflammatory response to surgical energy usage in laparoscopic surgery: results of a randomized study.Surgical endoscopy · 2016Trial
- Outcomes of laparoscopic cholecystectomy done with surgical energy versus done without surgical energy: a prospective-randomized control study.Surgical endoscopy · 2014Trial
- Efficacy of turmeric (curcumin) in pain and postoperative fatigue after laparoscopic cholecystectomy: a double-blind, randomized placebo-controlled study.Surgical endoscopy · 2011Trial
- Effect of Curcumin in Experimental Peritonitis.The Indian journal of surgery · 2015Article
- Fast Track Surgery-Minimizing Side Effects of Surgery.The Indian journal of surgery · 2015Article
- Tasty and healthy TR(i)Ps. The human quest for culinary pungency.EMBO reports · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative pain is a concern for patients seeking hemorrhoid surgery. Stapled hemorrhoidopexy is popular due to better patient-reported outcomes (PROs). Pain is the index of PROs. Posthemorrhoidectomy patients usually opt for a spice-free diet due to fear of pain or anal pruritus induced by spices. Curcumin and peprin (spice constituents) have powerful antiinflammatory and antioxidant properties. Ability to resume a normal taste-habituated meal may improve PRO quality of life. Thus, spice-related paradoxic conservatism in stapled hemorrhoidopexy, which involves no open wound, needed to be studied.
methodsA prospective open-ended study (July 2008 to August 2009) investigated consecutive candidates for day-care stapled hemorrhoidopexy randomized by the date of birth method into a controlled group (receiving a spices-free diet) and a study group (receiving a spicy diet) after an ethics and informed consent protocol. A standard perioperative protocol was followed. At discharge, the patients were advised to resume a normal diet (spicy or bland) and instructed to maintain a pain diary (100-point visual analog scale [VAS]) and an analgesic diary. Paracetamol 650 mg was used for pain exceeding a VAS score of 25. Patients were followed on day 3 and weeks 1 and 3. Failure to be discharged from day care, failure to maintain patient diary, and squamous epithelium in the rectal donut were the withdrawal criteria.
resultsA total of 67 patients were randomized. The groups were well matched for demographics, comorbidities, types of anesthesia, hemorrhoidal grades, and withdrawal. Statistically significant improvement in PROs (P<0.05) and a lower consumption of analgesic tablets were seen in the study group (spicy diet). No adverse event was reported in either group.
conclusionResumption of a spicy diet has no adverse impact on PROs after stapled hemorrhoidopexy. Reduced analgesic usage in the spicy diet study group needs to be evaluated further for any potential benefits of spices.
Indexed as
Identifiers
20976480What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.