Evidence map›Paper›PMID 20976081›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2011

Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud.

Rajesh Arora, R Chawla, Rohit Marwah, P Arora, R K Sharma, Vinod Kaushik, R Goel, A Kaur, M Silambarasan, R P Tripathi and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04341688 (A Double Blind, Randomized Controlled Pilot Trial of Gargling Agents in Reducing Intraoral Viral Load Among Laboratory Confirmed COVID-19 Patients), which is not on this map. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04341688 naunknown statusnot on this mapstarted 2021, after this paper: background citation

A Double Blind, Randomized Controlled Pilot Trial of Gargling Agents in Reducing Intraoral Viral Load Among Laboratory Confirmed COVID-19 Patients: GARGLES STUDY

TypeinterventionalSponsorAga Khan UniversityRan2021 to 2022Enrolled50ConditionsCovid-19ArmsGargle/Mouthwash
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Cocos nucifera (L.) (Arecaceae): A phytochemical and pharmacological review.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2015
    Pooled it
  5. Trial
  6. Article
  7. Ayurvedic and Chinese Herbs against Coronaviruses.Current pharmaceutical design · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Plants (Basel, Switzerland) · 2022
    Review
  13. Article
  14. Chewing Gums as a Drug Delivery Approach for Oral Health.International journal of dentistry · 2022
    Review
  15. Review
  16. Article
  17. Ayurveda Rasayana as antivirals and immunomodulators: potential applications in COVID-19.Environmental science and pollution research international · 2021
    Review
  18. Review
  19. Review
  20. Potential of Malawi's medicinal plants in Covid-19 disease management: A review.Malawi medical journal : the journal of Medical Association of Malawi · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rajesh AroraDivision of Chemical Biological, Radiological and Nuclear (CBRN) Defence, Institute of Nuclear Medicine and Allied Sciences, Defence Research and Development Organization, Brig. S.K. Mazumdar Road, Delhi 110054, India.
R Chawla
Rohit Marwah
P Arora
R K Sharma
Vinod Kaushik
R Goel
A Kaur
M Silambarasan
R P Tripathi
J R Bhardwaj

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of novel H1N1 has posed a situation that warrants urgent global attention. Though antiviral drugs are available in mainstream medicine for treating symptoms of swine flu, currently there is no preventive medicine available. Even when available, they would be in short supply and ineffective in a pandemic situation, for treating the masses worldwide. Besides the development of drug resistance, emergence of mutant strains of the virus, emergence of a more virulent strain, prohibitive costs of available drugs, time lag between vaccine developments, and mass casualties would pose difficult problems. In view of this, complementary and alternative medicine (CAM) offers a plethora of interesting preventive possibilities in patients. Herbs exhibit a diverse array of biological activities and can be effectively harnessed for managing pandemic flu. Potentially active herbs can serve as effective anti influenza agents. The role of CAM for managing novel H1N1 flu and the mode of action of these botanicals is presented here in an evidence-based approach that can be followed to establish their potential use in the management of influenza pandemics. The complementary and alternative medicine approach deliberated in the paper should also be useful in treating the patients with serious influenza in non pandemic situations.

Identifiers

PMID20976081
PMCPMC2957173

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.