Evidence map›Paper›PMID 20976035›Full record

ArticleAnalytical methods : advancing methods and applications2010

Qualitative and quantitative analysis of retinol, retinyl esters, tocopherols and selected carotenoids out of various internal organs form different species by HPLC.

Michael W Schäffer, Somdutta Sinha Roy, Shyamali Mukherjee, Donatus Nohr, Michael Wolter, Hans K Biesalski, David E Ong, Salil K Das

Open access · greenAbstract read
In one paragraph

Article in Analytical methods : advancing methods and applications, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Michael W SchäfferMeharry Medical College, Dept. of Biochemistry and Cancer Biology, 1005, Dr. D.B. Todd, Jr. Blvd., Nashville, TN 37208, U.S.A.
Somdutta Sinha Roy
Shyamali Mukherjee
Donatus Nohr
Michael Wolter
Hans K Biesalski
David E Ong
Salil K Das
Meharry Medical College · USUniversity of Hohenheim · DEVanderbilt University Medical Center · US

Funding

Abnormality in Gene Expression of Key Mediators of Vitamin A Action in COPDR03HL095419 · NHLBI · MEHARRY MEDICAL COLLEGE · PI DAS, SALIL K · 2009 to 2010
$147k
NHLBI NIH HHS R03 HL095419
6 · The paper itself

Abstract

We report the validation of a reversed-phase gradient HPLC method allowing simultaneous quantification of retinol, retinyl esters, tocopherols and selected carotenoids in lung, liver and plasma of mouse, rat and guinea pig (gp) using a diode array detector. A significant species difference was observed regarding the distribution of retinol and retinyl esters. The levels of total retinol in lung, liver and plasma were in the following order: mouse >> rat > gp; rat >mouse > gp; and gp >> rat > mouse, respectively. Furthermore, comparison studies revealed similarities between the vitamin A profiles of human and gp lung samples.

Identifiers

PMID20976035
PMCPMC2957904
OpenAlexW2171778945

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.