ArticleInternational journal of biological sciences2010
Gene expression profiling of skeletal muscle of nursing piglets.
Article in International journal of biological sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 49 citations in OpenAlex.
- microRNA Temporal-Specific Expression Profiles Reveal longissimus dorsi Muscle Development in Tianzhu White Yak.International journal of molecular sciences · 2024Article
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- LncRNAs and their regulatory networks in breast muscle tissue of Chinese Gushi chickens during late postnatal development.BMC genomics · 2021Article
- Transcriptomic profile of leg muscle during early growth and development in Haiyang yellow chicken.Archives animal breeding · 2021Article
- Spliced genes in muscle from Nelore Cattle and their association with carcass and meat quality.Scientific reports · 2020Article
- RAPID COMMUNICATION: Residual feed intake in beef cattle is associated with differences in protein turnover and nutrient transporters in ruminal epithelium.Journal of animal science · 2019Article
- Analyses of MicroRNA and mRNA Expression Profiles Reveal the Crucial Interaction Networks and Pathways for Regulation of Chicken Breast Muscle Development.Frontiers in genetics · 2019Article
- RNA-Seq transcriptome analysis of breast muscle in Pekin ducks supplemented with the dietary probiotic Clostridium butyricum.BMC genomics · 2018Article
- Whole genome scan reveals the genetic signature of African Ankole cattle breed and potential for higher quality beef.BMC genetics · 2017Article
- Article
- A Genome-Wide mRNA Screen and Functional Analysis Reveal FOXO3 as a Candidate Gene for Chicken Growth.PloS one · 2015Article
- Characterization, tissue expression, and imprinting analysis of the porcine CDKN1C and NAP1L4 genes.Journal of biomedicine & biotechnology · 2012Article
- Porcine tissue-specific regulatory networks derived from meta-analysis of the transcriptome.PloS one · 2012Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To gain insight into the regulation mechanism associated with the rapid gain in skeletal muscle during neonatal period, gene expression profiles of skeletal muscle of nursing pigs was investigated using Affymetrix Porcine GeneChip. A total of 1094 transcripts were detected as differential expression over time course tested (p<0.01, q<0.05). With combinative use of partitioning around medoid and hierarchical clustering, three clusters of transcripts with distinct temporal expression were defined. Gene functional categories and pathways, particularly involved in cell signaling, cell cycle, cell adhesion, ECM-receptor interaction, glycolysis, protein synthesis and degradation, and intracellular transport, were identified. Moreover, we showed 49 of the differentially expressed genes within published QTL regions or with marked deletion effects. Our study demonstrates previously uncharacterized changes in transcription accompanying early postnatal growth of skeletal muscle of pigs. It has highlighted potential cascades and important candidates for further investigation on controlling of postnatal muscle growth.
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