ArticleNature neuroscience2010
Epigenetic regulation of the neural transcriptome: the meaning of the marks.
Article in Nature neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
94 citing papers in PubMed.
- HIV associated epigenetic trends and chronic diseases: insights into the hidden burden of chronic infection.Clinical epigenetics · 2026Review
- Review
- Genetic Foundations of Inter-individual Neurophysiological Variability.bioRxiv : the preprint server for biology · 2025Article
- Modulating neuroplasticity for chronic pain relief: noninvasive neuromodulation as a promising approach.Experimental & molecular medicine · 2025Review
- Investigating sex differences in developmental origins of adolescent depression.Frontiers in child and adolescent psychiatry · 2025Article
- Gut microbiota, nutrition, and mental health.Frontiers in nutrition · 2024Review
- Review
- Child DNA methylation in a randomised controlled trial of a video-feedback intervention to promote positive parenting and sensitive discipline (VIPP-SD).Frontiers in child and adolescent psychiatry · 2023Article
- Article
- Epigenetic Targeting of Histone Deacetylases in Diagnostics and Treatment of Depression.International journal of molecular sciences · 2021Review
- HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.eLife · 2021Article
- Article
- The role of the genome in experience-dependent plasticity: Extending the analogy of the genomic action potential.Proceedings of the National Academy of Sciences of the United States of America · 2020Review
- Epigenetic regulation of neuronal cell specification inferred with single cell "Omics" data.Computational and structural biotechnology journal · 2020Article
- Trauma-Informed Care in Pediatrics: A Developmental Perspective in Twelve Cases with Narratives.The Permanente journal · 2020Review
- Early-Life Adversity Induces Epigenetically Regulated Changes in Hippocampal Dopaminergic Molecular Pathways.Molecular neurobiology · 2019Article
- Deep Neural Network Classifier for Virtual Screening Inhibitors of (S)-Adenosyl-L-Methionine (SAM)-Dependent Methyltransferase Family.Frontiers in chemistry · 2019Article
- Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018Article
- Involvement of Epigenetic Modifications of GABAergic Interneurons in Basolateral Amygdala in Anxiety-like Phenotype of Prenatally Stressed Mice.The international journal of neuropsychopharmacology · 2018Article
- Restoring Tip60 HAT/HDAC2 Balance in the Neurodegenerative Brain Relieves Epigenetic Transcriptional Repression and Reinstates Cognition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The field of epigenetics provides neurobiologists with candidate mechanisms for experience-dependent changes in gene transcription. The ability to realize the potential of epigenetics in defining the causal pathways lying between environmental signals, transcriptional regulation and neural function will depend on moving beyond correlational studies focusing on individual epigenetic marks. Here we attempt to provide a conceptual framework for integrative research on nucleotide sequence, chromatin modifications, RNA signaling and their interactions in understanding experience-dependent phenotypic plasticity. Studies in genomic imprinting may serve as an existing model for such approaches.
Indexed as
Identifiers
20975754What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.