Evidence map›Paper›PMID 20975708›Full record

ArticleNature communications2010

Motion-based DNA detection using catalytic nanomotors.

Jie Wu, Shankar Balasubramanian, Daniel Kagan, Kalayil Manian Manesh, Susana Campuzano, Joseph Wang

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Nature communications, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 313 citations in OpenAlex.

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  12. Mechanochemical active ratchet.Scientific reports · 2023
    Article
  13. Review
  14. Article
  15. Article
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  20. Tailoring Functional Micromotors for Sensing.Research (Washington, D.C.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jie WuDepartment of Nanoengineering, University of California San Diego, La Jolla, CA 92093, USA.
Shankar Balasubramanian
Daniel Kagan
Kalayil Manian Manesh
Susana Campuzano
Joseph Wang
University of California, San Diego · US

Funding

Sensor Technology for Rapid Microbial Identification and Susceptibility TestingU01AI075565 · NIAID · BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE · PI HAAKE, DAVID A · 2007 to 2011
$3.3M
NIAID NIH HHS U01 AI075565
6 · The paper itself

Abstract

Synthetic nanomotors, which convert chemical energy into autonomous motion, hold considerable promise for diverse applications. In this paper, we show the use of synthetic nanomotors for detecting DNA and bacterial ribosomal RNA in a fast, simple and sensitive manner. The new motion-driven DNA-sensing concept relies on measuring changes in the speed of unmodified catalytic nanomotors induced by the dissolution of silver nanoparticle tags captured in a sandwich DNA hybridization assay. The concentration-dependent distance signals are visualized using optical microscopy, particularly through straight-line traces by magnetically aligned 'racing' nanomotors. This nanomotor biodetection strategy could be extended to monitor a wide range of biomolecular interactions using different motion transduction schemes, thus providing a versatile and powerful tool for detecting biological targets.

Indexed as

Biosensing TechniquesDNAMetal NanoparticlesModels, TheoreticalNanostructuresNanotechnologySilverDNASilver

Identifiers

PMID20975708
OpenAlexW2000640150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.