Evidence map›Paper›PMID 20975278›Full record

ArticleFetal diagnosis and therapy2010

Assessment of left ventricular pre-ejection period in the fetus using simultaneous magnetocardiography and echocardiography.

Nana Aba Mensah-Brown, Ronald T Wakai, Bageshree Cheulkar, Shardha Srinivasan, Janette F Strasburger

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Fetal diagnosis and therapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Assessment of atrioventricular conduction by echocardiography and magnetocardiography in normal and anti-Ro/SSA-antibody-positive pregnancies.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2019
    Article
  5. Article
  6. Review
  7. Article
  8. Cardiac time intervals derived by magnetocardiography in fetuses exposed to pregnancy hypertension syndromes.Journal of perinatology : official journal of the California Perinatal Association · 2016
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nana Aba Mensah-BrownDepartment of Medical Physics, University of Wisconsin, Madison, USA.
Ronald T Wakai
Bageshree Cheulkar
Shardha Srinivasan
Janette F Strasburger
Medical College of Wisconsin · USUniversity of Wisconsin–Madison · USUniversity of Wisconsin American Family Children's Hospital · US

Funding

Optimized Signal Processing of Fetal MCG R01HL063174 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI WAKAI, RONALD T · 1999 to 2020
$8.4M
Simultaneous Echocardiography & Magnetocardiography In Fetal Heart DiseaseR21HD049022 · NICHD · MEDICAL COLLEGE OF WISCONSIN · PI STRASBURGER, JANETTE F · 2006 to 2007
$308k
NHLBI NIH HHS R01 HL063174NHLBI NIH HHS R01HL63174NICHD NIH HHS R21 HD049022NICHD NIH HHS R21HD049022
6 · The paper itself

Abstract

introductionFetal magnetocardiography (fMCG) is a promising new technique for assessing fetal rhythm; however, no prior studies have utilized fMCG to evaluate human fetal electromechanical physiology. Pre-ejection period (PEP) is an important measure of the electromechanical activation of the heart, and is altered by disease states and arrhythmias. MATERIALS AND

methodsA novel technique was used to assess fetal PEP and its relationship to other fetal systolic time intervals, RR interval, and gestational age (GA). 25 normal human fetuses between 19 and 38 weeks' gestation were studied using simultaneous pulsed Doppler ultrasound and fMCG. Correlations among PEP, ejection time, QRS width and RR interval were assessed using linear regression.

resultsAcross all subjects, PEP was found to correlate with GA (R = 0.57, p < 0.0001), QRS width (R = 0.35, p = 0.026), and RR interval (R = 0.37, p = 0.018). In individual sessions, PEP negatively correlated beat-to-beat with the preceding RR interval.

conclusionPEP exhibits developmental trends that provide a better understanding of the normal development of the human fetal heart.

Indexed as

Echocardiography, DopplerHeart Rate, FetalMagnetocardiographyStroke VolumeVentricular FunctionFemaleFetal HeartGestational AgeHeart VentriclesHumansPregnancySystole

Identifiers

PMID20975278
PMCPMC2992646
OpenAlexW2015677588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.