Evidence map›Paper›PMID 20974478›Full record

ArticleJournal of psychiatric research2011

Impact of broadening definitions of anorexia nervosa on sample characteristics.

Jocilyn E Dellava, Laura M Thornton, Paul Lichtenstein, Nancy L Pedersen, Cynthia M Bulik

Abstract read
In one paragraph

Article in Journal of psychiatric research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Recovery From Anorexia Nervosa: A Concept Analysis.Journal of advanced nursing · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Reconceptualizing anorexia nervosa.Psychiatry and clinical neurosciences · 2019
    Review
  13. Review
  14. Article
  15. Article
  16. DSM-IV-defined anorexia nervosa versus subthreshold anorexia nervosa (EDNOS-AN).European eating disorders review : the journal of the Eating Disorders Association · 2013
    Article
  17. Common psychiatric disorders and caffeine use, tolerance, and withdrawal: an examination of shared genetic and environmental effects.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2012
    Article
  18. Article
  19. Article
  20. Genetics and Epigenetics of Eating Disorders.Advances in genomics and genetics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jocilyn E DellavaDepartment of Psychiatry, University of North Carolina at Chapel Hill, CB #7160, 101 Manning Drive, Chapel Hill, NC 27599-7160, USA.
Laura M Thornton
Paul Lichtenstein
Nancy L Pedersen
Cynthia M Bulik

Funding

GENETIC &ENVIRONMENT DETERMINANTS OF SMOKING CESSATIONR01CA085739 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI SULLIVAN, PATRICK F · 2001 to 2006
$3.1M
Interstitial Cystitis in Swedish TwinsU01DK066134 · NIDDK · KAROLINSKA INSTITUTE · PI PEDERSEN, NANCY L · 2004 to 2008
$2.9M
Postdoctoral Research Training in Eating DisordersT32MH076694 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M · 2007 to 2016
$1.8M
NCI NIH HHS R01 CA085739NIDDK NIH HHS DK UO1 DK 066134NIDDK NIH HHS U01 DK066134NIMH NIH HHS T32 MH076694NIMH NIH HHS T32MH076694-03
6 · The paper itself

Abstract

Practical limitations and sample size considerations often lead to broadening of diagnostic criteria for anorexia nervosa (AN) in research. The current study sought to elucidate the effects of this practice on resultant sample characteristics in terms of eating disorder behaviors, psychiatric comorbidities, temperament and personality characteristics, and heritability point estimates. Three definitions of AN were created: meeting all Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) criteria for AN (AN-DSM-IV), meeting all DSM-IV criteria except criterion D, amenorrhea, (AN-noD), and broadening DSM-IV AN criteria by allowing a higher body mass index value, eliminating criterion D, and allowing less stringent body weight concerns (AN-Broad). Using data from the Swedish Twin Registry, 473 women fit one of the three definitions of AN. Women with AN-DSM-IV reported significantly more eating disorder behaviors than women with AN-Broad. Women with AN-noD reported more comorbid psychiatric disorders than women with AN-DSM-IV and AN-Broad. Temperament and personality characteristics did not differ across the three groups. Heritability point estimates decreased as AN definition broadened. Broadening the diagnostic criteria for AN results in an increased number of individuals available for participation in research studies. However, broader criteria for AN yield a more heterogeneous sample with regard to eating disorder symptoms and psychiatric comorbidity than a sample defined by narrower criteria.

Indexed as

Sampling StudiesAdultAnorexia NervosaDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMiddle AgedPrevalencePsychiatric Status Rating ScalesTwin Studies as TopicYoung Adult

Identifiers

PMID20974478
PMCPMC3033482

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.