ArticleClinical research in cardiology : official journal of the German Cardiac Society2011
Impact of minimising door-to-balloon times in ST-elevation myocardial infarction to less than 30 min on outcome: an analysis over an 8-year period in a tertiary care centre.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 19 citations in OpenAlex.
- Culprit lesion location and outcome in patients with cardiogenic shock complicating myocardial infarction: a substudy of the IABP-SHOCK II-trial.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Trial
- A prospective, randomized trial of continuous lateral rotation ("kinetic therapy") in patients with cardiogenic shock.Clinical research in cardiology : official journal of the German Cardiac Society · 2012Trial
- TNF-α, myocardial perfusion and function in patients with ST-segment elevation myocardial infarction and primary percutaneous coronary intervention.Clinical research in cardiology : official journal of the German Cardiac Society · 2012Trial
- Maladaptive hypertrophy after acute myocardial infarction positive effect of bone marrow-derived stem cell therapy on regional remodeling measured by cardiac MRI.Clinical research in cardiology : official journal of the German Cardiac Society · 2011Trial
- Public Recognition of Emergencies and Appropriate Ambulance Use in Riyadh: A Cross-Sectional Survey.Healthcare (Basel, Switzerland) · 2025Article
- Mortality in Patients with Acute Coronary Syndrome-A Prospective 5-Year Follow-Up Study.Journal of clinical medicine · 2023Article
- Prognostic significance of emergency department bypass in stable and unstable patients with ST-segment elevation myocardial infarction.European heart journal. Acute cardiovascular care · 2020Article
- Occurrence and Impact of Time Delay to Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction.Cardiology research · 2017Article
- Delay from first medical contact to primary PCI and all-cause mortality: a nationwide study of patients with ST-elevation myocardial infarction.Journal of the American Heart Association · 2014Observational
- Short-term outcome of patients with ST-segment elevation myocardial infarction (STEMI) treated with an everolimus-eluting bioresorbable vascular scaffold.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Observational
- Efficacy and limitations of a STEMI network: 3 years of experience within the myocardial infarction network of the region of Augsburg - HERA.Clinical research in cardiology : official journal of the German Cardiac Society · 2013Article
- The patient's interpretation of myocardial infarction symptoms and its role in the decision process to seek treatment: the MONICA/KORA Myocardial Infarction Registry.Clinical research in cardiology : official journal of the German Cardiac Society · 2012Article
- First clinical evaluation of a novel capacitive ECG system in patients with acute myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2012Article
- Myocardial salvage in acute myocardial infarction--challenges in clinical translation.Journal of molecular and cellular cardiology · 2011Article
- As time goes by?: the fallacy of thrombolysis in STEMI networks.Clinical research in cardiology : official journal of the German Cardiac Society · 2011Article
- Incidence and distribution of occluded culprit arteries and impact of coronary collaterals on outcome in patients with non-ST-segment elevation myocardial infarction and early invasive treatment strategy.Clinical research in cardiology : official journal of the German Cardiac Society · 2011Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGuidelines recommend door-to-balloon times (DBTs) below 60 min for patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). The purpose of this study was to determine if an optimised STEMI-protocol reduces DBT and increases the number of patients to receive PCI within 60 min of hospital presentation. We hypothesised that DBT of <30 min can be accomplished for the majority of patients. METHODS AND
resultsBetween 2001 and 2008 data from 1,146 consecutive patients with acute STEMI admitted for primary PCI within 12 h after symptom-onset were analysed. Times to angioplasty from symptom-onset (pain-to-balloon time, PBT) and from hospital arrival (DBT) to PCI and clinical outcomes were analysed. In the end of 2003 numerous strategies were implemented to reduce revascularisation times. These strategies resulted in a stable reduction of median DBT to 29 min [interquartile range (IQR) 22-39]. Overall, 94% of patients had median DBT < 60 min and 56% <30 min. Consequently, PBT was significantly reduced from median 218 min (IQR 168-286) to 167 min (IQR 119-245) for non-transferred patients. Major cardiac adverse events (composite of congestive heart failure, reinfarction and cardiac death) were significantly associated with DBT > 30 min and age, systolic blood pressure, anterior infarction, PBT > 4 h, cardiogenic shock as well as multivessel disease.
conclusionsA dedicated STEMI-protocol including several hospital strategies is feasible during daily clinical practice to decrease revascularisation times, results in a greater proportion of patients achieving guideline recommendations, and is associated with an improved clinical outcome.
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