ArticleDie Naturwissenschaften2010
Macroglomeruli for fruit odors change blend preference in Drosophila.
Article in Die Naturwissenschaften, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 62 citations in OpenAlex.
- Article
- Comparative single-cell transcriptomic atlases of drosophilid brains suggest glial evolution during ecological adaptation.PLoS biology · 2025Article
- Olfactory sensory neuron population expansions influence projection neuron adaptation and enhance odour tracking.Nature communications · 2024Article
- Evolution of connectivity architecture in the Drosophila mushroom body.Nature communications · 2024Article
- Odor-regulated oviposition behavior in an ecological specialist.Nature communications · 2023Article
- Review
- Rapid brain development and reduced neuromodulator titres correlate with host shifts inRoyal Society open science · 2022Article
- The genomic basis of army ant chemosensory adaptations.Molecular ecology · 2021Article
- A reversal in sensory processing accompanies ongoing ecological divergence and speciation inProceedings. Biological sciences · 2021Article
- Does Divergence in Habitat Breadth Associate with Species Differences in Decision Making inGenes · 2020Article
- Evolution of olfactory circuits in insects.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2020Review
- How a fly came to love the vomit fruit.Nature · 2020Article
- Article
- Review
- Evolution of Reproductive Behavior.Genetics · 2020Review
- Molecular and Functional Evolution at the Odorant Receptor Or22 Locus in Drosophila melanogaster.Molecular biology and evolution · 2019Article
- Patterns of transcriptional parallelism and variation in the developing olfactory system of Drosophila species.Scientific reports · 2017Article
- Odorant receptors and antennal lobe morphology offer a new approach to understanding olfaction in the Asian longhorned beetle.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2017Article
- The Evolution of Olfactory Gene Families in Drosophila and the Genomic Basis of chemical-Ecological Adaptation in Drosophila suzukii.Genome biology and evolution · 2016Article
- Synaptic circuitry of identified neurons in the antennal lobe of Drosophila melanogaster.The Journal of comparative neurology · 2016Article
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The olfactory circuitry of Drosophila melanogaster is becoming increasingly clear. However, how olfactory processing translates into appropriate behavioral responses is still poorly understood. Using a sibling species approach, we tested how a perturbation in the olfactory circuitry affects odor preference. In a previous study, we found that the sibling species of D. melanogaster, the specialist D. sechellia, overrepresents a sensillum, ab3, the A neuron of which is sensitive to hexanoate esters, characteristic of the species' sole host, the Morinda citrifolia fruit. Concordantly, the corresponding glomerulus, DM2, is enlarged. In this study, we found that the ab3B neuron, the expansion of which was previously assumed to be pleiotropic and of no ecological significance, is in fact tuned to another morinda fruit volatile, 2-heptanone (HP). Axons of this neuron type arborize in a second enlarged glomerulus. In behavioral experiments we tested how this has affected the fly's odor preference. We demonstrate that D. sechellia has a reversed preference for the key ligands of these macroglomeruli, especially at high concentrations. Whereas D. melanogaster was repelled by high concentrations of these odors, D. sechellia was highly attracted. This was the case for odors presented singly, but more notably for blends thereof. Our study indicates that relatively simple changes, such as a shift in sensillar abundance, and concordant shifts in glomerular size, can distort the resulting olfactory code, and can lead to saltatory shifts in odor preference. D. sechellia has exploited this to align its olfactory preference with its ecological niche.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.