Evidence map›Paper›PMID 20972641›Full record

ArticleJournal of general internal medicine2011

Ability to walk 1/4 mile predicts subsequent disability, mortality, and health care costs.

Susan E Hardy, Yihuang Kang, Stephanie A Studenski, Howard B Degenholtz

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Journal of general internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03430271 (ENhancing Independence Using Group-based Community Interventions for Healthy AGing in Elders), which is not on this map. Cited by 178 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
178citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03430271 nacompletednot on this mapstarted 2015, after this paper: background citation

ENhancing Independence Using Group-based Community Interventions for Healthy AGing in Elders: The ENGAGE Pilot Study

TypeinterventionalSponsorTufts UniversityRan2015 to 2016Enrolled59ConditionsMobility LimitationArmsPhysical Activity Intervention, Healthy Aging Intervention
3 · Its place in the literature

Who cites it

178 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Trial
  6. Biomarkers of Cellular Senescence Predict the Onset of Mobility Disability and Are Reduced by Physical Activity in Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Trial
  7. Trial
  8. Global Positioning System Indicators of Community Mobility and Future Health Outcomes Among Older Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Trial
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  12. Association Between Improved Mobility and Distal Health Outcomes.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Trial
  13. Effect of Losartan and Fish Oil on Plasma IL-6 and Mobility in Older Persons. The ENRGISE Pilot Randomized Clinical Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Trial
  14. Trial
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  16. A Comparison of Self-report Indices of Major Mobility Disability to Failure on the 400-m Walk Test: The LIFE Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018
    Trial
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118 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Susan E HardyUniversity of Pittsburgh School of Medicine, 3471 Fifth Avenue, Suite 500, Pittsburgh, PA 15213, USA. seh46@pitt.edu
Yihuang Kang
Stephanie A Studenski
Howard B Degenholtz

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Functional Recovery in Post-Acute CareK23AG030977 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARDY, SUSAN E · 2008 to 2012
$545k
Post-acute Care and Functional Recovery after HospitalizationR03AG032291 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HARDY, SUSAN E · 2008 to 2009
$124k
NCATS NIH HHS UL1 TR000005NIA NIH HHS K23 AG030977NIA NIH HHS K23AG030977NIA NIH HHS P30 AG-024827NIA NIH HHS P30 AG024827NIA NIH HHS R03 AG032291NIA NIH HHS R03AG032291
6 · The paper itself

Abstract

backgroundMobility, such as walking 1/4 mile, is a valuable but underutilized health indicator among older adults. For mobility to be successfully integrated into clinical practice and health policy, an easily assessed marker that predicts subsequent health outcomes is required.

objectiveTo determine the association between mobility, defined as self-reported ability to walk 1/4 mile, and mortality, functional decline, and health care utilization and costs during the subsequent year.

designAnalysis of longitudinal data from the 2003-2004 Medicare Current Beneficiary Survey, a nationally representative sample of Medicare beneficiaries.

participantsParticipants comprised 5895 community-dwelling adults aged 65 years or older enrolled in Medicare. MAIN MEASURES: Mobility (self-reported ability to walk 1/4 mile), mortality, incident difficulty with activities of daily living (ADLs), total annual health care costs, and hospitalization rates. KEY

resultsAmong older adults, 28% reported difficulty and 17% inability to walk 1/4 mile at baseline. Compared to those without difficulty and adjusting for demographics, socioeconomic status, chronic conditions, and health behaviors, mortality was greater in those with difficulty [AOR (95% CI): 1.57 (1.10-2.24)] and inability [AOR (CI): 2.73 (1.79-4.15)]. New functional disability also occurred more frequently as self-reported ability to walk 1/4 mile declined (subsequent incident disability among those with no difficulty, difficulty, or inability to walk 1/4 mile at baseline was 11%, 29%, and 47% for instrumental ADLs, and 4%, 14%, and 23% for basic ADLs). Total annual health care costs were $2773 higher (95% CI $1443-4102) in persons with difficulty and $3919 higher (CI $1948-5890) in those who were unable. For each 100 persons, older adults reporting difficulty walking 1/4 mile at baseline experienced an additional 14 hospitalizations (95% CI 8-20), and those who were unable experienced an additional 22 hospitalizations (CI 14-30) during the follow-up period, compared to persons without walking difficulty.

conclusionsMobility disability, a simple self-report measure, is a powerful predictor of future health, function, and utilization independent of usual health and demographic indicators. Mobility disability may be used to target high-risk patients for care management and preventive interventions.

Indexed as

Mobility LimitationPersons with DisabilitiesActivities of Daily LivingAgedDisability EvaluationFemaleHealth Care CostsHumansLongitudinal StudiesMaleMortalityPredictive Value of TestsRisk FactorsSelf ReportWalking

Identifiers

PMID20972641
PMCPMC3019329

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.