ArticlePlant physiology2010
Fine quantitative trait loci mapping of carbon and nitrogen metabolism enzyme activities and seedling biomass in the maize IBM mapping population.
Article in Plant physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 65 citations in OpenAlex.
- Association Mapping for Evaluation of Population Structure, Genetic Diversity, and Physiochemical Traits in Drought-Stressed Maize Germplasm Using SSR Markers.Plants (Basel, Switzerland) · 2023Article
- Effect of polyaspartic acid and different dosages of controlled-release fertilizers on nitrogen uptake, utilization, and yield of maize cultivars.Bioengineered · 2021Article
- Heterotic quantitative trait loci analysis and genomic prediction of seedling biomass-related traits in maize triple testcross populations.Plant methods · 2021Article
- Characterization of effects of genetic variants via genome-scale metabolic modelling.Cellular and molecular life sciences : CMLS · 2021Review
- Univariate and Multivariate QTL Analyses Reveal Covariance Among Mineral Elements in the Rice Ionome.Frontiers in genetics · 2021Article
- Recent Advances in Carbon and Nitrogen Metabolism in C3 Plants.International journal of molecular sciences · 2020Review
- Meiotic crossovers characterized by haplotype-specific chromosome painting in maize.Nature communications · 2019Article
- Multivariate analysis reveals environmental and genetic determinants of element covariation in the maize grain ionome.Plant direct · 2019Article
- Biochemical and genetic analyses of N metabolism in maize testcross seedlings: 2. Roots.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Genome-Wide Association Mapping Reveals That Specific and Pleiotropic Regulatory Mechanisms Fine-Tune Central Metabolism and Growth in Arabidopsis.The Plant cell · 2017Article
- Biochemical and genetic analyses of N metabolism in maize testcross seedlings: 1. Leaves.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- The Interaction of Genotype and Environment Determines Variation in the Maize Kernel Ionome.G3 (Bethesda, Md.) · 2016Article
- Nitrogen assimilation system in maize is regulated by developmental and tissue-specific mechanisms.Plant molecular biology · 2016Article
- Regions of the bread wheat D genome associated with variation in key photosynthesis traits and shoot biomass under both well watered and water deficient conditions.Journal of applied genetics · 2016Article
- Correlation-Based Network Analysis of Metabolite and Enzyme Profiles Reveals a Role of Citrate Biosynthesis in Modulating N and C Metabolism in Zea mays.Frontiers in plant science · 2016Article
- An ultra-high-density map as a community resource for discerning the genetic basis of quantitative traits in maize.BMC genomics · 2015Article
- The Nitrate-Inducible NAC Transcription Factor TaNAC2-5A Controls Nitrate Response and Increases Wheat Yield.Plant physiology · 2015Article
- AGPase: its role in crop productivity with emphasis on heat tolerance in cereals.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Review
- Genome-wide association of carbon and nitrogen metabolism in the maize nested association mapping population.Plant physiology · 2015Article
- A genetic relationship between nitrogen use efficiency and seedling root traits in maize as revealed by QTL analysis.Journal of experimental botany · 2015Article
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Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the genetic basis of nitrogen and carbon metabolism will accelerate the development of plant varieties with high yield and improved nitrogen use efficiency. A robotized platform was used to measure the activities of 10 enzymes from carbon and nitrogen metabolism in the maize (Zea mays) intermated B73 × Mo17 mapping population, which provides almost a 4-fold increase in genetic map distance compared with conventional mapping populations. Seedling/juvenile biomass was included to identify its genetic factors and relationships with enzyme activities. All 10 enzymes showed heritable variation in activity. There were strong positive correlations between activities of different enzymes, indicating that they are coregulated. Negative correlations were detected between biomass and the activity of six enzymes. In total, 73 significant quantitative trait loci (QTL) were found that influence the activity of these 10 enzymes and eight QTL that influence biomass. While some QTL were shared by different enzymes or biomass, we critically evaluated the probability that this may be fortuitous. All enzyme activity QTL were in trans to the known genomic locations of structural genes, except for single cis-QTL for nitrate reductase, Glu dehydrogenase, and shikimate dehydrogenase; the low frequency and low additive magnitude compared with trans-QTL indicate that cis-regulation is relatively unimportant versus trans-regulation. Two-gene epistatic interactions were identified for eight enzymes and for biomass, with three epistatic QTL being shared by two other traits; however, epistasis explained on average only 2.8% of the genetic variance. Overall, this study identifies more QTL at a higher resolution than previous studies of genetic variation in metabolism.
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