Evidence map›Paper›PMID 20970974›Full record

ReviewCurrent opinion in immunology2011

Diverse roles of non-diverse molecules: MHC class Ib molecules in host defense and control of autoimmunity.

Amelia R Hofstetter, Lucy C Sullivan, Aron E Lukacher, Andrew G Brooks

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. The Loss of HLA-F/KIR3DS1 Ligation Is Mediated by Hemoglobin Peptides.International journal of molecular sciences · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Genetics and autoantibodies.Immunologic research · 2013
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amelia R HofstetterDepartment of Pathology, Emory University School of Medicine, Atlanta, GA 30322, United States.
Lucy C Sullivan
Aron E Lukacher
Andrew G Brooks

Funding

T CELL IMMUNITY TO POLYOMA VIRUS INDUCED TUMORSR01CA071971 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LUKACHER, ARON ELIOT · 2001 to 2011
$3.0M
Analysis of MHC Class Ib-Restricted Polyoma Virus-Specific CD8 T CellsR01CA139220 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LUKACHER, ARON ELIOT · 2009 to 2013
$1.6M
Regulation of Polyoma Virus-Specific CD8+ T CellsR01CA100644 · NCI · EMORY UNIVERSITY · PI LUKACHER, ARON · 2003 to 2007
$1.4M
NCI NIH HHS R01 CA071971NCI NIH HHS R01 CA100644NCI NIH HHS R01 CA139220NCI NIH HHS R01 CA71971
6 · The paper itself

Abstract

While the prime function of classical MHC class I molecules (MHC-I) is to present peptide antigens to pathogen-specific cytotoxic T cells, non-classical MHC-I antigens perform a diverse array of functions in both innate and adaptive immunity. In this review we summarize recent evidence that non classical MHC-I molecules are not only recognized by pathogen-specific T cells but that they also serve as immunoregulatory molecules by stimulating a number of distinct non-conventional T cell subsets.

Indexed as

AutoimmunityAdaptive ImmunityAnimalsHistocompatibility Antigens Class IHumansImmunity, InnateT-LymphocytesHistocompatibility Antigens Class I

Identifiers

PMID20970974
PMCPMC4254846

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.