ArticleJournal of the American Academy of Child and Adolescent Psychiatry2010
Adult outcomes of childhood dysregulation: a 14-year follow-up study.
Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers, 8 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
150 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Early Predictors of the Childhood Dysregulation Profile: A Systematic Review.Clinical child and family psychology review · 2026Pooled it
- Systematic review: the impact of maternal pre-and postnatal cannabis use on the behavioral and emotional regulation in early childhood.European child & adolescent psychiatry · 2025Pooled it
- Prevalence and comorbidity rates of disruptive mood dysregulation disorder in epidemiological and clinical samples: systematic review and meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- A systematic review of virtual reality therapies for substance use disorders: Impact on secondary treatment outcomes.The American journal on addictions · 2023Pooled it
- Suicidal behaviors and irritability in children and adolescents: a systematic review of the nature and mechanisms of the association.European child & adolescent psychiatry · 2019Pooled it
- The Status of Irritability in Psychiatry: A Conceptual and Quantitative Review.Journal of the American Academy of Child and Adolescent Psychiatry · 2016Pooled it
- Do childhood externalizing disorders predict adult depression? A meta-analysis.Journal of abnormal child psychology · 2014Pooled it
- Evidence Base Update on the Assessment of Irritability, Anger, and Aggression in Youth.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Pooled it
- A Double-Blind Randomized Placebo-Controlled Trial of Citalopram Adjunctive to Stimulant Medication in Youth With Chronic Severe Irritability.Journal of the American Academy of Child and Adolescent Psychiatry · 2020Trial
- Dysregulation in Youth with Anxiety Disorders: Relationship to Acute and 7- to 19- Year Follow-Up Outcomes of Cognitive-Behavioral Therapy.Child psychiatry and human development · 2016Trial
- Predictors of Change in Severity of Self-Injurious Behaviors in Preschool-Aged Autistic Children.Autism research : official journal of the International Society for Autism Research · 2026Article
- The Impact of Maternal Emotion Talk on an Early Intervention for Infants with Elevated Levels of Behavior Problems.Child psychiatry and human development · 2026Article
- Patterns of psychopathology and personal strengths among youth in psychiatric care.JCPP advances · 2026Article
- The Dysregulation Profile and Substance Use: Investigating Their Co-Variation From Adolescence to Emerging Adulthood.Emerging adulthood (Print) · 2026Article
- Article
- Clinical Characterization of Emotional Dysregulation in Adults with and Without ADHD: A Cross-Sectional Multigroup Comparative Study.Brain sciences · 2026Article
- Associations of Tonic and Phasic Irritability With Psychopathology Subfactors of the Hierarchical Taxonomy of Psychopathology.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Neonatal Brain Volumes and Early Parenting Behavior as Mediators in Associations Between Prenatal Social Disadvantage and Socioemotional Problems in Toddlers.Biological psychiatry · 2026Article
- Stability and change of psychopathology symptoms among youth with chronic physical illness: A latent transition analysis.Clinical child psychology and psychiatry · 2026Article
- Reactivity and regulation of negative and positive emotions in child- and adolescent diagnostic and trait-level ADHD: a cross-sectional study.BMC psychiatry · 2025Article
90 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
objectiveUsing a general population sample, the adult outcomes of children who presented with severe problems with self-regulation defined as being concurrently rated highly on attention problems, aggressive behavior, and anxious-depression on the Child Behavior Checklist-Dysregulation Profile (CBCL-DP) were examined.
methodTwo thousand seventy-six children from 13 birth cohorts 4 to 16 years of age were drawn from Dutch birth registries in 1983. CBCLs were completed by parents at baseline when children from the different cohorts were 4 to 16 years of age and sampled every 2 years for the next 14 years. At year 14 the CBCL and DSM interview data were collected. Logistic regression was used to compare and contrast outcomes for children with and without dysregulation, as measured by the latent-class-defined CBCL-DP. Sex and age were covaried and concurrent DSM diagnoses were included in regression models.
resultsPresence of childhood CBCL-DP at wave 1 was associated with increased rates of adult anxiety disorders, mood disorders, disruptive behavior disorders, and drug abuse 14 years later. After controlling for co-occurring disorders in adulthood, associations with anxiety and disruptive behavior disorders with the CBCL-DP remained, whereas the others were not significant.
conclusionsA child reported to be in the CBCL-DP class is at increased risk for problems with regulating affect, behavior, and cognition in adulthood.
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