ArticleBMC genomics2010
Copy number variation in the porcine genome inferred from a 60 k SNP BeadChip.
Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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Who cites it
67 citing papers in PubMed, 111 citations in OpenAlex.
- Article
- Unveiling the Influence of Copy Number Variations on Genetic Diversity and Adaptive Evolution in China's Native Pig Breeds via Whole-Genome Resequencing.International journal of molecular sciences · 2024Article
- Copy Number Variation onMicrobiology spectrum · 2023Article
- Copy Number Variation Regions Differing in Segregation Patterns Span Different Sets of Genes.Animals : an open access journal from MDPI · 2023Article
- An effect of large-scale deletions and duplications on transcript expression.Functional & integrative genomics · 2022Article
- Genome-wide evaluation of copy gain and loss variations in three Afghan sheep breeds.Scientific reports · 2022Article
- Two Different Copy Number Variations of theAnimals : an open access journal from MDPI · 2021Article
- Genome-Wide Assessment Characteristics of Genes Overlapping Copy Number Variation Regions in Duroc Purebred Population.Frontiers in genetics · 2021Article
- Tracing selection signatures in the pig genome gives evidence for selective pressures on a unique curly hair phenotype in Mangalitza.Scientific reports · 2020Article
- A genome-wide analysis of copy number variation in Murciano-Granadina goats.Genetics, selection, evolution : GSE · 2020Article
- CNV analysis of Meishan pig by next-generation sequencing and effects ofJournal of animal science and biotechnology · 2020Article
- Identification of copy number variations using high density whole-genome SNP markers in Chinese Dongxiang spotted pigs.Asian-Australasian journal of animal sciences · 2019Article
- About the existence of common determinants of gene expression in the porcine liver and skeletal muscle.BMC genomics · 2019Article
- A large interactive visual database of copy number variants discovered in taurine cattle.GigaScience · 2019Article
- A genome-wide single nucleotide polymorphism and copy number variation analysis for number of piglets born alive.BMC genomics · 2019Article
- A Survey of Copy Number Variation in the Porcine Genome Detected From Whole-Genome Sequence.Frontiers in genetics · 2019Article
- Copy number variation in livestock: A mini review.Veterinary world · 2018Review
- Genome-wide analysis reveals differential selection involved with copy number variation in diverse Chinese Cattle.Scientific reports · 2017Article
- CNV discovery for milk composition traits in dairy cattle using whole genome resequencing.BMC genomics · 2017Article
- A smart sealed nucleic acid biosensor based on endogenous reference gene detection to screen and identify mammals on site.Scientific reports · 2017Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent studies in pigs have detected copy number variants (CNVs) using the Comparative Genomic Hybridization technique in arrays designed to cover specific porcine chromosomes. The goal of this study was to identify CNV regions (CNVRs) in swine species based on whole genome SNP genotyping chips.
resultsWe used predictions from three different programs (cnvPartition, PennCNV and GADA) to analyze data from the Porcine SNP60 BeadChip. A total of 49 CNVRs were identified in 55 animals from an Iberian x Landrace cross (IBMAP) according to three criteria: detected in at least two animals, contained three or more consecutive SNPs and recalled by at least two programs. Mendelian inheritance of CNVRs was confirmed in animals belonging to several generations of the IBMAP cross. Subsequently, a segregation analysis of these CNVRs was performed in 372 additional animals from the IBMAP cross and its distribution was studied in 133 unrelated pig samples from different geographical origins. Five out of seven analyzed CNVRs were validated by real time quantitative PCR, some of which coincide with well known examples of CNVs conserved across mammalian species.
conclusionsOur results illustrate the usefulness of Porcine SNP60 BeadChip to detect CNVRs and show that structural variants can not be neglected when studying the genetic variability in this species.
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