Evidence map›Paper›PMID 20969536›Full record

ReviewJournal of neurovirology2010

Foamy virus: an available vector for gene transfer in neural cells and other nondividing cells.

Yingying Zhang, Yongjuan Liu, Guoguo Zhu, Yanyan Qiu, Biwen Peng, Jun Yin, Wanhong Liu, Xiaohua He

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neurovirology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. The Use ofFrontiers in veterinary science · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yingying ZhangSchool of Medicine, Wuhan University, Wuchang, Wuhan, China.
Yongjuan Liu
Guoguo Zhu
Yanyan Qiu
Biwen Peng
Jun Yin
Wanhong Liu
Xiaohua He
Wuhan University · CNWuhan Donghu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foamy viruses (FVs) are classified to a subfamily of retrovirus presented in a wide range of hosts. None of FVs has been found to associate with any diseases in their native hosts. Such a unique biological character of FVs makes it suitable for the development of vectors for gene transfer. However, it is still controversial whether foamy virus vectors (FV vectors) can be applied to the central nervous system (CNS). In this review, we summarize the studies of FV vectors, which have been used for transduction of neural cells and other nondividing cells. We further discuss the potential mechanisms underlying the infection and propose that FVs can be used to develop transfer vectors for gene therapy in neurological disorders.

Indexed as

Gene Transfer TechniquesAnimalsCell LineCentral Nervous SystemGenetic TherapyGenetic VectorsHumansNeuronsRatsSpumavirusTransduction, Genetic

Identifiers

PMID20969536
OpenAlexW2156072036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.