Evidence map›Paper›PMID 20969465›Full record

ArticleAIDS patient care and STDs2010

Mortality after diagnosis of psychiatric disorders and co-occurring substance use disorders among HIV-infected patients.

Gerald N DeLorenze, Derek D Satre, Charles P Quesenberry, Ai-Lin Tsai, Constance M Weisner

Registry-linked trialAbstract read
In one paragraph

Article in AIDS patient care and STDs, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01671501 (Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01671501 nacompletednot on this mapstarted 2013, after this paper: background citation

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

TypeinterventionalSponsorUniversity of California, San FranciscoRan2013 to 2017Enrolled614ConditionsHIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic IntoxicationArmsMotivational Interviewing, Email Feedback, Usual Care
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Impact of Abstinence and of Reducing Illicit Drug Use Without Abstinence on Human Immunodeficiency Virus Viral Load.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gerald N DeLorenzeDivision of Research , Kaiser Permanente Northern California, Oakland, California 94612, USA. gerald.n.delorenze@kp.org
Derek D Satre
Charles P Quesenberry
Ai-Lin Tsai
Constance M Weisner

Funding

Integrated Drug and Medical Care-Cost and EffectivenessR37DA010572 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEISNER, CONSTANCE M. · 2001 to 2010
$4.7M
Improving Alcohol and Drug Services for Older AdultsK23AA015411 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SATRE, DEREK D · 2005 to 2009
$684k
NIAAA NIH HHS K23 AA015411NIDA NIH HHS R37 DA10572)
6 · The paper itself

Abstract

We examined the associations between psychiatric diagnoses, substance use disorders, health services, and mortality among 9751 HIV-infected patients (≥14 years old) in a large, private medical care program, in a retrospective cohort design over a 12-year period. All study data were extracted from computerized clinical and administrative databases. Results showed that 25.4% (n = 2472) of the 9751 study subjects had received a psychiatric diagnosis (81.1% had major depression, 17.1% had panic disorder, 14.2% had bipolar disorder, and 8.1% had anorexia/bulimia); and 25.5% (n = 2489) had been diagnosed with substance use disorder; 1180 (12.1%) patients had received both psychiatric and substance diagnoses. In comparison to patients with neither a psychiatric diagnosis nor a SU diagnosis, the highest risk of death was found among patients with dual psychiatric and substance use diagnoses who had no psychiatric treatment visits and no substance treatment (relative hazards [RH] = 4.17, 95% confidence interval [CI] = 2.35 to 7.40). Among dually diagnosed patients, receiving psychiatric and/or substance use disorder treatment somewhat reduced the risk of death compared to patients with neither diagnosis. The lowest risks of death were observed among patients with a single diagnosis who had received corresponding treatment. Our study findings suggest that screening for psychiatric and substance problems at the initiation and during the course of HIV/AIDS treatment and providing psychiatric and substance use disorder treatment may extend life for these vulnerable patients.

Indexed as

AdolescentAdultBipolar DisorderCause of DeathDiagnosis, Dual (Psychiatry)FemaleHIV InfectionsHumansMajor Depressive DisorderMaleMental DisordersMental Health ServicesMiddle AgedPanic DisorderSubstance-Related DisordersYoung Adult

Identifiers

PMID20969465
PMCPMC2994548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.