Evidence map›Paper›PMID 20967875›Full record

ReviewWiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Nanoparticles as magnetic resonance imaging contrast agents for vascular and cardiac diseases.

Wei Chen, David P Cormode, Zahi A Fayad, Willem J M Mulder

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Carbon Dots Meet MRI: Metal Doping for a Smart Contrast Agent Design.International journal of molecular sciences · 2026
    Review
  3. Review
  4. Nanomaterial-based contrast agents.Nature reviews. Methods primers · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Nanoparticles for Cardiovascular Imaging and Therapeutic Delivery, Part 2: Radiolabeled Probes.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2015
    Review
  11. Article
  12. Multimodality PET/MRI agents targeted to activated macrophages.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2014
    Article
  13. Review
  14. Review
  15. Review
  16. Nanoformulations for molecular MRI.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
  17. Polymer-based therapeutics: nanoassemblies and nanoparticles for management of atherosclerosis.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wei ChenTranslational and Molecular Imaging Institute, Mount Sinai School of Medicine, New York, NY, USA.
David P CormodeTranslational and Molecular Imaging Institute, Mount Sinai School of Medicine, New York, NY, USA.
Zahi A FayadTranslational and Molecular Imaging Institute, Mount Sinai School of Medicine, New York, NY, USA.
Willem J M MulderTranslational and Molecular Imaging Institute, Mount Sinai School of Medicine, New York, NY, USA.

Funding

Theranostic HDL nanoparticles for inflammatory macrophages in atherosclerosisR01EB009638 · NIBIB · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FAYAD, ZAHI A. · 2009 to 2016
$4.6M
Theranostic nanoparticles to enhance morpholino delivery to the liver for suppresK99EB012165 · NIBIB · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CORMODE, DAVID PETER · 2010 to 2011
$179k
NIBIB NIH HHS K99 EB012165NIBIB NIH HHS R01 EB009638
6 · The paper itself

Abstract

Advances in nanoparticle contrast agents for molecular imaging have made magnetic resonance imaging a promising modality for noninvasive visualization and assessment of vascular and cardiac disease processes. This review provides a description of the various nanoparticles exploited for imaging cardiovascular targets. Nanoparticle probes detecting inflammation, apoptosis, extracellular matrix, and angiogenesis may provide tools for assessing the risk of progressive vascular dysfunction and heart failure. The utility of nanoparticles as multimodal probes and/or theranostic agents has also been investigated. Although clinical application of these nanoparticles is largely unexplored, the potential for enhancing disease diagnosis and treatment is considerable.

Indexed as

AnimalsCardiovascular DiseasesContrast MediaHumansLiposomesMagnetic Resonance ImagingMagnetite NanoparticlesContrast MediaLiposomesMagnetite Nanoparticles

Identifiers

PMID20967875
PMCPMC3256288

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.