ReviewPediatric nephrology (Berlin, Germany)2011
Intradialytic hypotension.
Review in Pediatric nephrology (Berlin, Germany), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03504943 (Timing of Intradialytic Exercise and Its Impact on Intradialytic Hypotension), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Timing of Intradialytic Exercise and Its Impact on Intradialytic Hypotension: a Randomized Crossover Study
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Evolution and change in paradigm of hemodialysis in children: a systematic review.Pediatric nephrology (Berlin, Germany) · 2021Pooled it
- Adequacy of dialysis in children and adolescents: more than just Kt/V.Pediatric nephrology (Berlin, Germany) · 2026Review
- Intradialytic Hypotensive Episodes are Only Occasionally Associated With Adverse Symptoms.Kidney international reports · 2026Article
- Renal replacement therapy in intensive care unit: a narrative review.Annals of intensive care · 2026Review
- Updates in the management of intradialytic hypotension: Emerging strategies and innovations.World journal of nephrology · 2025Review
- Hypereosinophilia-associated acute intradialytic hypotension: a report of three cases and literature review.CEN case reports · 2024Review
- Prospective Study of Modifiable Risk Factors of Arterial Hypertension and Left Ventricular Hypertrophy in Pediatric Patients on Hemodialysis.Kidney international reports · 2024Article
- Intradialytic Hypotension and Mortality in Adolescents and Young Adults With Kidney Failure Receiving Maintenance Hemodialysis.Kidney medicine · 2024Article
- Enhancing the Cardiovascular Safety of Hemodialysis Care Using Multimodal Provider Education and Patient Activation Interventions: Protocol for a Cluster Randomized Controlled Trial.JMIR research protocols · 2023Article
- Why is Intradialytic Hypotension the Commonest Complication of Outpatient Dialysis Treatments?Kidney international reports · 2023Review
- Lessons for the clinical nephrologist: an uncommon cause of rigors and chills on dialysis.Journal of nephrology · 2022Article
- Bedside sonographic assessments for predicting predialysis fluid overload in children with end-stage kidney disease.European journal of pediatrics · 2021Article
- Feeling better on hemodialysis: user-centered design requirements for promoting patient involvement in the prevention of treatment complications.Journal of the American Medical Informatics Association : JAMIA · 2021Article
- Usability Evaluation of a Tablet-Based Intervention to Prevent Intradialytic Hypotension in Dialysis Patients During In-Clinic Dialysis: Mixed Methods Study.JMIR human factors · 2021Article
- Cramping, crashing, cannulating, and clotting: a qualitative study of patients' definitions of a "bad run" on hemodialysis.BMC nephrology · 2020Article
- Pediatric intradialytic hypotension: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) Workgroup.Pediatric nephrology (Berlin, Germany) · 2019Article
- Assessment and management of fluid overload in children on dialysis.Pediatric nephrology (Berlin, Germany) · 2019Review
- Hemodialysis in children with ventriculoperitoneal shunts: prevalence, management and outcomes.Pediatric nephrology (Berlin, Germany) · 2016Article
- Lower Dialysate Temperature in Hemodialysis: Is It a Cool Idea?Clinical journal of the American Society of Nephrology : CJASN · 2015Article
- The accuracy of a continuous volumetric balancing system in pediatric continuous renal replacement therapy.The International journal of artificial organs · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intradialytic hypotension (IDH) is common in children during conventional, 4 hour haemodialysis (HD) sessions. The declining blood pressure (BP) was originally believed to be caused by ultrafiltration (UF) and priming of the HD circuit, however emerging data now supports a multifactorial aetiology. Therefore strategies to improve haemodynamic stability need to be diverse and address specific patient requirements or risks. In the treatment of IDH immediate action is required to stop or reduce the severity of symptoms that may precede or follow. Typically UF is slowed or stopped, a fluid bolus is given and in resistant cases the HD session is prematurely discontinued. Patients complete their treatment under-dialysed and volume expanded. Chronically, repeated episodes of IDH cause devastating, multi-system morbidity with an increased risk of mortality. This had provided the impetus for more haemodynamically friendly dialysis prescriptions that attenuate the risk of IDH. During pediatric HD several preventative strategies have been tested but with variable success. Of these, dialysate sodium profiling, UF guided by relative blood volume (RBV) algorithms, cooling and intradialytic mannitol appear to be the most effective. However in refractory cases one may be left with no option but to switch dialysis modality to haemodiafiltration (HDF) or more frequent or prolonged HD regimens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.