Evidence map›Paper›PMID 20967497›Full record

ArticleJournal of assisted reproduction and genetics2011

Spontaneous in vitro maturation and artificial activation of human germinal vesicle oocytes recovered from stimulated cycles.

Laura Escrich, Noelia Grau, Amparo Mercader, Carmen Rubio, Antonio Pellicer, María-José Escribá

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Embryological aspects of oocyte in vitro maturation.International journal of molecular and cellular medicine · 2013
    Review
  11. Article
  12. Article
  13. Article
  14. DECREASED FERTILIZATION: HUMAN SPERM DNA FRAGMENTATION ANDActa endocrinologica (Bucharest, Romania : 2005)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura EscrichUniversitary Institute IVI Valencia, Valencia, Spain.
Noelia Grau
Amparo Mercader
Carmen Rubio
Antonio Pellicer
María-José Escribá

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo define germinal vesicles (GV) by morphometric and morphologic examination and by chromatin compaction and to assess their spontaneous nuclear and cytoplasmic competence. MATERIALS: 131 GV were cultured for 42.7 ± 2.4 h. Nuclear maturation was evaluated at four time points. Sixty-seven in vitro and twenty-five in vivo metaphase II (MII) were activated. Parthenotes with 2 PB and one pronucleus (NA) were studied for ploidy.

resultsA total of 74.8% GV matured to MII: 55% at 21.4 ± 2.4 h and 47.3% in the following 24 h. Artificial activation induced NA in 79.2% of in vivo-MII and in 22.4% of in vitro-MII. All NA were haploid.

conclusionsGV spontaneously mature at the nuclear level. Their NA are haploid, but their cytoplasmic competence is compromised. Variables were not found to be predictors of oocyte competence, probably due to our population being homogeneous with respect to most of the variables studied.

Indexed as

AdultCalcimycinCell NucleusChromatinCytoplasmFemaleHumansIonophoresKaryotypingMeiosisMetaphaseOocytesPregnancyPuromycinCalcimycinChromatinIonophoresPuromycin

Identifiers

PMID20967497
PMCPMC3059530

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.