ArticlePlanta2011
Dwarf apple MbDREB1 enhances plant tolerance to low temperature, drought, and salt stress via both ABA-dependent and ABA-independent pathways.
Article in Planta, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 1 of them a synthesis that pooled it.
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Who cites it
85 citing papers in PubMed, 1 synthesis or guideline pooled it, 242 citations in OpenAlex.
- Comparative meta-analysis of barely transcriptome: Pathogen type determines host preference.PloS one · 2025Pooled it
- Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate-resilient apple breeding.Journal of integrative plant biology · 2026Article
- Genome-Wide Identification of DREB Gene Family in Kiwifruit and Functional Characterization of Exogenous 5-ALA-Mediated Cold Tolerance via ROS Scavenging and Hormonal Signaling.Plants (Basel, Switzerland) · 2025Article
- Physiological changes and full-length transcriptome of Artemisia sphaerocephala in response to drought stress.BMC plant biology · 2025Article
- A tubby-like protein, MdTLP7 enhances drought and salt stresses tolerance of Malus domestica.BMC plant biology · 2025Article
- Characterization of Critical Amino Acids in the Transport and Selectivity of the Plant NaInternational journal of molecular sciences · 2025Article
- Overexpression of aInternational journal of molecular sciences · 2025Article
- Evaluation of Salt Resistance of Six Apple Rootstocks.International journal of molecular sciences · 2024Article
- Upregulation of Wheat Heat Shock Transcription FactorInternational journal of molecular sciences · 2024Article
- Genome-wide identification and expression analysis of protein arginine methyltransferase and JmjC domain-containing family in apple.Frontiers in plant science · 2024Article
- Is calcium deficiency the real cause of bitter pit? A review.Frontiers in plant science · 2024Review
- MdNAC104 positively regulates apple cold tolerance via CBF-dependent and CBF-independent pathways.Plant biotechnology journal · 2023Article
- The Transcription Factor MbWRKY46 inInternational journal of molecular sciences · 2023Article
- Insights into the molecular mechanisms underlying responses of apple trees to abiotic stresses.Horticulture research · 2023Article
- Transcription factors MhDREB2A/MhZAT10 play a role in drought and cold stress response crosstalk in apple.Plant physiology · 2023Article
- Genome-Wide Identification, Evolution, and Expression Analyses of AP2/ERF Family Transcription Factors inInternational journal of molecular sciences · 2023Article
- Functional Characterization ofInternational journal of molecular sciences · 2023Article
- Urea derivative MTU improves stress tolerance and yield in wheat by promoting cyclic electron flow around PSI.Frontiers in plant science · 2023Article
- Biotechnological Interventions in Tomato (Biotech (Basel (Switzerland)) · 2022Review
- Identification of Functional Genetic Variations Underlying Flooding Tolerance in Brazilian Soybean Genotypes.International journal of molecular sciences · 2022Article
25 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In higher plants, DREB1/CBF-type transcription factors play an important role in tolerance to low temperatures, drought, and high-salt stress. These transcription factors bind to CRT/DRE elements in promoter regions of target genes, regulating their expression. In this study, we cloned and characterized a novel gene encoding a DREB1 transcription factor from dwarf apple, Malus baccata (GenBank accession number: EF582842). Expression of MbDREB1 was induced by cold, drought, and salt stress, and also in response to exogenous ABA. Subcellular localization analyses revealed that MbDREB1 localizes in the nucleus. A yeast activity assay demonstrated that the MbDREB1 gene encodes a transcription activator, which specifically binds to DRE/CRT elements. Compared with wild-type plants, transgenic Arabidopsis overexpressing MbDREB1 showed increased tolerance to low temperature, drought, and salt stresses. Analysis of the MbDREB1 promoter revealed an ABA-responsive element (ABRE), an inducer of CBF expression 1 (ICE1)-like binding site, two MYB recognition sites, and three stress-inducible GT-1 boxes. GUS activities driven by the MbDREB1 promoter in transgenic Arabidopsis increased in response to ABA, cold temperature, drought, and salt treatments. Interestingly, the expression of both ABA-independent and ABA-dependent stress-induced genes (COR15a and rd29B, respectively) was activated under normal growth conditions in Arabidopsis overexpressing MbDREB1. These results suggest that MbDREB1 functions as a transcription factor and increases plant tolerance to low temperature, drought, and salt stress via both ABA-dependent and ABA-independent pathways.
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