Evidence map›Paper›PMID 20967447›Full record

ArticleCurrent microbiology2011

Characterization of novel alleles of toxin co-regulated pilus A gene (tcpA) from environmental isolates of Vibrio cholerae.

Praveen Kumar, Anuja Thulaseedharan, Gautam Chowdhury, Thandavarayan Ramamurthy, Sabu Thomas

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Article in Current microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Applied and environmental microbiology · 2026
    Article
  2. Pan-Genome Analysis ofFrontiers in veterinary science · 2021
    Article
  3. Novel Cholera Toxin Variant and ToxT Regulon in EnvironmentalApplied and environmental microbiology · 2019
    Article
  4. Review
  5. Occurrence in Mexico, 1998-2008, of Vibrio cholerae CTX+ El Tor carrying an additional truncated CTX prophage.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Praveen KumarDepartment of Molecular Microbiology, Cholera and Environmental Microbiology Laboratory, Rajiv Gandhi Centre for Biotechnology, Trivandrum, Kerala, India.
Anuja Thulaseedharan
Gautam Chowdhury
Thandavarayan Ramamurthy
Sabu Thomas
Rajiv Gandhi Centre for Biotechnology · INNational Institute of Cholera and Enteric Diseases · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vibrio cholerae is causative agent of life threatening diarrheal disease, cholera. The toxin co-regulated pilus (TCP) is a critical colonization factor of V. cholerae and it also serves as receptor for CTXФ. In this study, we describe nucleotide sequence of four novel alleles of tcpA gene from toxigenic and non-toxigenic V. cholerae isolated from environmental sources. The phylogenetic analysis of tcpA revealed that it is related to tcpA of newly emerged O1 strain and unrelated to tcpA of wild type (classical and El Tor strains). All strains showed variant tcpA and also harbored intact Vibrio Pathogenicity Island (VPI). The expression of all variant alleles was demonstrated by RT-PCR.

Indexed as

Polymorphism, GeneticAllelesDNA, BacterialEnvironmental MicrobiologyFimbriae ProteinsGene Expression ProfilingGenotypeHumansMolecular Sequence DataPhylogenyReverse Transcriptase Polymerase Chain ReactionSequence Analysis, DNAVibrio choleraeVirulence FactorsDNA, BacterialFimbriae ProteinsTcpA protein, Vibrio choleraeVirulence Factors

Identifiers

PMID20967447
OpenAlexW2051386338

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.