ArticlePloS one2010
Increased anion channel activity is an unavoidable event in ozone-induced programmed cell death.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 50 citations in OpenAlex.
- Reactive oxygen species- and nitric oxide-dependent regulation of ion and metal homeostasis in plants.Journal of experimental botany · 2023Article
- Early Cellular Responses Induced by Sedimentary Calcite-Processed Particles in Bright Yellow 2 Tobacco Cultured Cells.International journal of molecular sciences · 2020Article
- Ion Transport in Plant Cell Shrinkage During Death.Frontiers in cell and developmental biology · 2020Article
- Expression of IbVPE1 from sweet potato in Arabidopsis affects leaf development, flowering time and chlorophyll catabolism.BMC plant biology · 2019Article
- Methanol induces cytosolic calcium variations, membrane depolarization and ethylene production in arabidopsis and tobacco.Annals of botany · 2018Article
- Exposure to Ambient Air Pollution and Premature Rupture of Membranes.American journal of epidemiology · 2016Article
- Effect of ozone on intestinal epithelial homeostasis in a rat model.Rambam Maimonides medical journal · 2015Article
- Vacuolar processing enzyme in plant programmed cell death.Frontiers in plant science · 2015Review
- Mitigation of copper toxicity by DNA oligomers in green paramecia.Plant signaling & behavior · 2015Article
- Deciphering early events involved in hyperosmotic stress-induced programmed cell death in tobacco BY-2 cells.Journal of experimental botany · 2014Article
- Could FaRP-Like Peptides Participate in Regulation of Hyperosmotic Stress Responses in Plants?Frontiers in endocrinology · 2014Review
- Article
- Ozone-induced caspase-like activities are dependent on early ion channel regulations and ROS generation in Arabidopsis thaliana cells.Plant signaling & behavior · 2013Article
- Crosstalk between intracellular and extracellular salicylic acid signaling events leading to long-distance spread of signals.Plant cell reports · 2013Review
- The impact of global change factors on redox signaling underpinning stress tolerance.Plant physiology · 2013Article
- Peroxyacetyl nitrate-induced oxidative and calcium signaling events leading to cell death in ozone-sensitive tobacco cell-line.Plant signaling & behavior · 2012Article
- Lethal impacts of cigarette smoke in cultured tobacco cells.Tobacco induced diseases · 2011Article
- Superoxide generation catalyzed by the ozone-inducible plant peptides analogous to prion octarepeat motif.Plant signaling & behavior · 2011Article
- Production and removal of superoxide anion radical by artificial metalloenzymes and redox-active metals.Communicative & integrative biologyReview
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOzone is a major secondary air pollutant often reaching high concentrations in urban areas under strong daylight, high temperature and stagnant high-pressure systems. Ozone in the troposphere is a pollutant that is harmful to the plant. PRINCIPAL
findingsBy exposing cells to a strong pulse of ozonized air, an acute cell death was observed in suspension cells of Arabidopsis thaliana used as a model. We demonstrated that O(3) treatment induced the activation of a plasma membrane anion channel that is an early prerequisite of O(3)-induced cell death in A. thaliana. Our data further suggest interplay of anion channel activation with well known plant responses to O(3), Ca(2+) influx and NADPH-oxidase generated reactive oxygen species (ROS) in mediating the oxidative cell death. This interplay might be fuelled by several mechanisms in addition to the direct ROS generation by O(3); namely, H(2)O(2) generation by salicylic and abscisic acids. Anion channel activation was also shown to promote the accumulation of transcripts encoding vacuolar processing enzymes, a family of proteases previously reported to contribute to the disruption of vacuole integrity observed during programmed cell death. SIGNIFICANCE: Collectively, our data indicate that anion efflux is an early key component of morphological and biochemical events leading to O(3)-induced programmed cell death. Because ion channels and more specifically anion channels assume a crucial position in cells, an understanding about the underlying role(s) for ion channels in the signalling pathway leading to programmed cell death is a subject that warrants future investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.