ArticleObstetrics and gynecology2010
Depressive disorders during pregnancy: prevalence and risk factors in a large urban sample.
Article in Obstetrics and gynecology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers, 7 of them syntheses that pooled it.
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Who cites it
142 citing papers in PubMed, 7 syntheses or guidelines pooled it, 314 citations in OpenAlex.
- Panic disorder during pregnancy and the first three years after delivery: a systematic review.BMC pregnancy and childbirth · 2025Pooled it
- Prenatal Attachment and Perinatal Depression: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Prevalence and determinants of antenatal depression in Ethiopia: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Racial/Ethnic Disparities in Antenatal Depression in the United States: A Systematic Review.Maternal and child health journal · 2016Pooled it
- Web-based interventions for prevention and treatment of perinatal mood disorders: a systematic review.BMC pregnancy and childbirth · 2016Pooled it
- Identifying the women at risk of antenatal anxiety and depression: A systematic review.Journal of affective disorders · 2016Pooled it
- Maternal use of antidepressant or anxiolytic medication during pregnancy and childhood neurodevelopmental outcomes: a systematic review.European child & adolescent psychiatry · 2014Pooled it
- Mamma Mia - A randomized controlled trial of an internet-based intervention for perinatal depression.Psychological medicine · 2019Trial
- A prospective cohort study of antipsychotic medications in pregnancy: the first 147 pregnancies and 100 one year old babies.PloS one · 2014Trial
- Trial
- Long-term neuronal and neurocognitive consequences in offspring after prenatal exposure to a novel antidepressant, vilazodone: Role of BDNF/Bax-Bcl-2/AChE mediated pathways.Psychopharmacology · 2026Article
- Factors associated with postpartum depression symptoms following antepartum hospitalization.Pregnancy (Hoboken, N.J.) · 2026Article
- Validation of the Greek Version of Tilburg Pregnancy Distress Scale (TPDS).Advances in experimental medicine and biology · 2026Article
- Prevalence and associated factors of antenatal depression among pregnant women attending Shegaw Motta general Hospital, East Gojjam Zone, Ethiopia.Scientific reports · 2025Article
- Development and validation of a predictive nomogram for antenatal depression in China.BMC pregnancy and childbirth · 2025Article
- Country of Birth, Race, Ethnicity, and Prenatal Depression.JAMA network open · 2025Article
- Depressive symptoms among women of reproductive age with and without HIV in the Southern United States.AIDS (London, England) · 2025Observational
- Oral microbiome composition is associated with depressive symptoms during pregnancy.Brain, behavior, & immunity - health · 2025Article
- Women's mental health during late pregnancy: A survey conducted in Shandong Province, China.Fortschritte der Neurologie-Psychiatrie · 2025Article
- Voice analysis and deep learning for detecting mental disorders in pregnant women: a cross-sectional study.Discover mental health · 2025Article
82 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo estimate the prevalence of major and minor depression, panic disorder, and suicidal ideation during pregnancy while also identifying factors independently associated with antenatal depressive disorders.
methodsIn this prospective study, participants were 1,888 women receiving ongoing prenatal care at a university obstetric clinic from January 2004 through January 2009. Prevalence of psychiatric disorders was measured using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria based on the Patient Health Questionnaire. Multiple logistic regression identified factors associated with probable major depressive disorder and any depressive disorder.
resultsAntenatal depressive disorders were present in 9.9% with 5.1% (97) meeting criteria for probable major depression and 4.8% (90) meeting criteria for probable minor depression. Panic disorder was present in 3.2% (61), and current suicidal ideation was reported by 2.6% (49). Among patients with probable major depression, 29.5% (28) reported current suicidal ideation. Psychosocial stress (odds ratio [OR], 1.29; 95% confidence interval [CI], 1.21-1.36), domestic violence (OR 3.45; 95% CI 1.46-8.12), chronic medical conditions (OR 3.05; 95% CI 1.63-5.69), and race (Asian: OR 5.81; 95% CI 2.55-13.23; or African American: OR 2.98; 95% CI 1.24-7.18) each significantly increased the odds of probable antepartum major depressive disorder, whereas older age (OR 0.92; 95% CI 0.88-0.97) decreased the odds. Factors associated with odds of any depression were similar overall except that Hispanic ethnicity (OR 2.50; 95% CI 1.09-5.72) also independently increased the odds of any depression.
conclusionAntenatal major and minor depressive disorders are common and significantly associated with clinically relevant and identifiable risk factors. By understanding the high point prevalence and associated factors, clinicians can potentially improve the diagnosis and treatment rates of serious depressive disorders in pregnant women. LEVEL OF EVIDENCE: II.
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