ArticleBMC plant biology2010
Significance of Cuscutain, a cysteine protease from Cuscuta reflexa, in host-parasite interactions.
Article in BMC plant biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- The role of hormones in parasitic plant infection.Plant & cell physiology · 2026Review
- Pharmacological Properties of Parasitic Plants: Current Evidence and the Role of Parasitic Lifestyle.Plants (Basel, Switzerland) · 2026Review
- Current understanding of the role of the cell wall in Cuscuta parasitism.Plant biology (Stuttgart, Germany) · 2025Review
- Identification of a Papain-like Cysteine Protease Functioning as an Avirulence Factor in Striga-Cowpea Interactions.Plants (Basel, Switzerland) · 2025Article
- Proteomic characterization and cytotoxic potential of proteins from Cuscuta (Cuscuta epithymum (L.) crude herbal product against MCF-7 human breast cancer cell line.BMC complementary medicine and therapies · 2024Article
- Comparative secretome analysis of Striga and Cuscuta species identifies candidate virulence factors for two evolutionarily independent parasitic plant lineages.BMC plant biology · 2024Article
- Protein Profiling ofPlants (Basel, Switzerland) · 2023Article
- Article
- Genome-enabled discovery of candidate virulence loci in Striga hermonthica, a devastating parasite of African cereal crops.The New phytologist · 2022Article
- Physiology and molecular biology of plants : an international journal of functional plant biology · 2019Article
- Development of Parasitic Organs of a Stem Holoparasitic Plant in GenusFrontiers in plant science · 2019Review
- Appraisal of anti-arthritic and nephroprotective potential of Cuscuta reflexa.Pharmaceutical biology · 2017Article
- Activity of xyloglucan endotransglucosylases/hydrolases suggests a role during host invasion by the parasitic plant Cuscuta reflexa.PloS one · 2017Article
- Getting ready for host invasion: elevated expression and action of xyloglucan endotransglucosylases/hydrolases in developing haustoria of the holoparasitic angiosperm Cuscuta.Journal of experimental botany · 2016Article
- Comparative transcriptome analyses reveal core parasitism genes and suggest gene duplication and repurposing as sources of structural novelty.Molecular biology and evolution · 2015Article
- Parasitic plants of the genus Cuscuta and their interaction with susceptible and resistant host plants.Frontiers in plant science · 2015Review
- Molecular convergence of the parasitic plant species Cuscuta reflexa and Phelipanche aegyptiaca.Planta · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlant infestation with parasitic weeds like Cuscuta reflexa induces morphological as well as biochemical changes in the host and the parasite. These modifications could be caused by a change in protein or gene activity. Using a comparative macroarray approach Cuscuta genes specifically upregulated at the host attachment site were identified.
resultsOne of the infestation specific Cuscuta genes encodes a cysteine protease. The protein and its intrinsic inhibitory peptide were heterologously expressed, purified and biochemically characterized. The haustoria specific enzyme was named cuscutain in accordance with similar proteins from other plants, e.g. papaya. The role of cuscutain and its inhibitor during the host parasite interaction was studied by external application of an inhibitor suspension, which induced a significant reduction of successful infection events.
conclusionsThe study provides new information about molecular events during the parasitic plant--host interaction. Inhibition of cuscutain cysteine proteinase could provide means for antagonizing parasitic plants.
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