ReviewJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2010
Pes cavus and hereditary neuropathies: when a relationship should be suspected.
Review in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Unraveling the Genetic Landscape of Foot Arch Morphology: A Systematic Review of Single Nucleotide Polymorphisms.Clinical genetics · 2025Pooled it
- Inherited Peripheral Neuropathies.Neurologic clinics · 2025Review
- Signs and symptoms of carriers of non-Journal of neuromuscular diseases · 2025Article
- Utilization of artificial intelligence in the diagnosis of pes planus and pes cavus with a smartphone camera.World journal of orthopedics · 2024Article
- Quantitative Characterization of Gait Patterns in Individuals with Spinocerebellar Ataxia 38.Bioengineering (Basel, Switzerland) · 2023Article
- X-linked Charcot-Marie-Tooth disease with GJB1 mutation presenting as acute disseminated encephalomyelitis-like illness: A case report.Medicine · 2017Article
- A prospective study of midfoot osteotomy combined with adjacent joint sparing internal fixation in treatment of rigid pes cavus deformity.Journal of orthopaedic surgery and research · 2014Article
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Authors and funding
7 authors.
Funding
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Abstract
The hereditary peripheral neuropathies are a clinically and genetically heterogeneous group of diseases of the peripheral nervous system. Foot deformities, including the common pes cavus, but also hammer toes and twisting of the ankle, are frequently present in patients with hereditary peripheral neuropathy, and often represent one of the first signs of the disease. Pes cavus in hereditary peripheral neuropathies is caused by imbalance between the intrinsic muscles of the foot and the muscles of the leg. Accurate clinical evaluation in patients with pes cavus is necessary to exclude or confirm the presence of peripheral neuropathy. Hereditary peripheral neuropathies should be suspected in those cases with bilateral foot deformities, in the presence of family history for pes cavus and/or gait impairment, and in the presence of neurological symptoms or signs, such as distal muscle hypotrophy of limbs. Herein, we review the hereditary peripheral neuropathies in which pes cavus plays a key role as a "spy sign," discussing the clinical and molecular features of these disorders to highlight the importance of pes cavus as a helpful clinical sign in these rare diseases.
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