ArticlePlant cell reports2010
Silencing of Plum pox virus 5'UTR/P1 sequence confers resistance to a wide range of PPV strains.
Article in Plant cell reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- HTS analysis of resistance induction against PPV by four hairpin constructs in Nicotiana benthamiana Domin.Scientific reports · 2025Article
- Development and Validation of One-Step Reverse Transcription-Droplet Digital PCR for Plum Pox Virus Detection and Quantification from Plant Purified RNA and Crude Extract.Plants (Basel, Switzerland) · 2024Article
- CRISPR/Cas as a Genome-Editing Technique in Fruit Tree Breeding.International journal of molecular sciences · 2023Review
- Trans-grafting plum pox virus resistance from transgenic plum rootstocks to apricot scions.Frontiers in plant science · 2023Article
- Current achievements and future directions in genetic engineering of European plum (Prunus domestica L.).Transgenic research · 2018Review
- Citrus psorosis virus coat protein-derived hairpin construct confers stable transgenic resistance in citrus against psorosis A and B syndromes.Transgenic research · 2017Article
- Expression Analysis of Hairpin RNA CarryingBioMed research international · 2017Article
- Fighting Sharka in Peach: Current Limitations and Future Perspectives.Frontiers in plant science · 2016Article
- Biotechnological strategies and tools for Plum pox virus resistance: trans-, intra-, cis-genesis, and beyond.Frontiers in plant science · 2015Review
- Robust RNA silencing-mediated resistance to Plum pox virus under variable abiotic and biotic conditions.Molecular plant pathology · 2014Article
- Biosafety considerations of RNAi-mediated virus resistance in fruit-tree cultivars and in rootstock.Transgenic research · 2013Review
- Article
- Mechanisms, applications, and perspectives of antiviral RNA silencing in plants.Revista mexicana de fitopatologia : la revista oficial de la Sociedad Mexicana de FitopatologiaArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An effective disease-control strategy should protect the host from the major economically important and geographically widespread variants of a pathogen. Plum pox virus (PPV) is the causal agent of sharka, the most devastating viral disease of Prunus species. We have shown previously that the hairpin RNA expression driven by h-UTR/P1, h-P1/HCPro, h-HCPro and h-HCPro/P3 constructs, derived from the PPV-M ISPaVe44 isolate, confers resistance to the homologous virus in Nicotiana benthamiana plants. Since the production of transgenic stone fruits and their evaluation for PPV resistance would take several years, the ISPaVe44-resistant plant lines were used to evaluate which construct would be the best candidate to be transferred to Prunus elite cultivars. To do that, nine PPV isolates of the D, M, Rec, EA and C strains originally collected from five Prunus species in different geographical areas, were typed by sequencing and used to challenge the transgenic N. benthamiana lines; 464 out of 464 virus-inoculated plants of lines h-UTR/P1, h-HCPro and h-HCPro/P3 showed complete and long-lasting resistance to the seven PPV isolates of D, M and Rec strains. Moreover, the h-UTR/P1 plants were also fully resistant to PPV-C and -EA isolates. Our data suggest that the h-UTR/P1 construct is of particular practical interest to obtain stone fruit plants resistant to the sharka disease.
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