Evidence map›Paper›PMID 20962143›Full record

ArticleJournal of clinical microbiology2010

False-negative PCR result due to gene polymorphism: the example of Neisseria meningitidis.

Katia Jaton, Béatrice Ninet, Jacques Bille, Gilbert Greub

Abstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Limitation ofJournal of clinical microbiology · 2022
    Article
  4. Observational
  5. Article
  6. Article
  7. Towards multitarget testing in molecular microbiology.International journal of microbiology · 2013
    Review
  8. Comparison of PCR-based methods for the simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in clinical samples.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katia JatonInstitute of Microbiology, University Hospital of Lausanne (CHUV), Bugnon 48, 1011 Lausanne, Switzerland. Katia.Jaton-Ogay@chuv.ch
Béatrice Ninet
Jacques Bille
Gilbert Greub

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early treatment of meningococcal meningitis is mandatory but may negate the cerebrospinal fluid culture. Etiological diagnosis then mainly relies on PCR. Here, we report a case of false-negative results for real-time PCR for a Neisseria meningitidis serogroup B isolate with a polymorphism in the ctrA gene.

Indexed as

False Negative ReactionsPolymorphism, GeneticBacterial ProteinsBacteriological TechniquesChild, PreschoolDNA, BacterialHumansMaleMeningococcal InfectionsMolecular Sequence DataNeisseria meningitidisPolymerase Chain ReactionSequence Analysis, DNABacterial ProteinsDNA, Bacterial

Identifiers

PMID20962143
PMCPMC3008480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.