ArticleJournal of the American Medical Informatics Association : JAMIA
Impact of generic substitution decision support on electronic prescribing behavior.
Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effect of Electronic Prescribing Compared to Paper-Based (Handwritten) Prescribing on Primary Medication Adherence in an Outpatient Setting: A Systematic Review.Applied clinical informatics · 2021Pooled it
- Influencers of generic drug utilization: A systematic review.Research in social & administrative pharmacy : RSAP · 2018Pooled it
- Behaviour change interventions to promote prescribing of generic drugs: a rapid evidence synthesis and systematic review.BMJ open · 2014Pooled it
- Are ACOs Ready to be Accountable for Medication Use?Journal of managed care & specialty pharmacy · 2020Article
- INN or brand name drug prescriptions: a multilevel, cross-sectional study in general practice.European journal of clinical pharmacology · 2019Article
- ePrescribing: Reducing Costs through In-Class Therapeutic Interchange.Applied clinical informatics · 2016Article
- Giving formulary and drug cost information to providers and impact on medication cost and use: a longitudinal non-randomized study.BMC health services research · 2016Article
- Effects of an e-Prescribing interface redesign on rates of generic drug prescribing: exploiting default options.Journal of the American Medical Informatics Association : JAMIA · 2016Article
- Paying physicians to prescribe generic drugs and follow-on biologics in the United States.PLoS medicine · 2015Article
- Effect of electronic prescribing with formulary decision support on medication tier, copayments, and adherence.BMC medical informatics and decision making · 2014Article
- Building a web-based tool to support clinical decisions in the control of Chlamydia trachomatis and Neisseria gonorrhoeae infections.BMC proceedings · 2013Article
- Electronic prescribing in pediatrics: toward safer and more effective medication management.Pediatrics · 2013Review
- Generic medications and blood pressure control in diabetic hypertensive subjects: results from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.Diabetes care · 2013Article
- Users' satisfaction with the primary health care information system in Croatia: a cross-sectional study.Croatian medical journal · 2012Article
- Impact of clinical decision support on receipt of antibiotic prescriptions for acute bronchitis and upper respiratory tract infection.Journal of the American Medical Informatics Association : JAMIAArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectiveTo evaluate the impact of generic substitution decision support on electronic (e-) prescribing of generic medications.
designThe authors analyzed retrospective outpatient e-prescribing data from an academic medical center and affiliated network for July 1, 2005-September 30, 2008 using an interrupted time-series design to assess the rate of generic prescribing before and after implementing generic substitution decision support. To assess background secular trends, e-prescribing was compared with a concurrent random sample of hand-generated prescriptions. MEASUREMENTS: Proportion of generic medications prescribed before and after the intervention, evaluated over time, and compared with a sample of prescriptions generated without e-prescribing.
resultsThe proportion of generic medication prescriptions increased from 32.1% to 54.2% after the intervention (22.1% increase, 95% CI 21.9% to 22.3%), with no diminution in magnitude of improvement post-intervention. In the concurrent control group, increases in proportion of generic prescriptions (29.3% to 31.4% to 37.4% in the pre-intervention, post-intervention, and end-of-study periods, respectively) were not commensurate with the intervention. There was a larger change in generic prescribing rates among authorized prescribers (24.6%) than nurses (18.5%; adjusted OR 1.38, 95% CI 1.17 to 1.63). Two years after the intervention, the proportion of generic prescribing remained significantly higher for e-prescriptions (58.1%; 95% CI 57.5% to 58.7%) than for hand-generated prescriptions ordered at the same time (37.4%; 95% CI 34.9% to 39.9%) (p<0.0001). Generic prescribing increased significantly in every specialty.
conclusionImplementation of generic substitution decision support was associated with dramatic and sustained improvements in the rate of outpatient generic e-prescribing across all specialties.
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