Evidence map›Paper›PMID 20960540›Full record

ArticleClinical cardiology2010

Association of left atrial myocardial function with left ventricular diastolic dysfunction in subjects with preserved systolic function: a strain rate imaging study.

Zhiqiang Guan, Di Zhang, Rongjie Huang, Fang Zhang, Qingrong Wang, Shenglan Guo

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
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  4. Left Atrial Strain in Pediatric Cardiology: Evidence to Date and Future Directions.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2026
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  16. La Tunisie medicale · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zhiqiang GuanDepartment of Ultrasound, the First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. China.
Di ZhangDepartment of Ultrasound, the First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. China.
Rongjie HuangDepartment of Cardiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. China.
Fang ZhangDepartment of Electrocardiography, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Qingrong WangDepartment of Ultrasound, the First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. China.
Shenglan GuoDepartment of Ultrasound, the First Affiliated Hospital of Guangxi Medical University, Nanning, P. R. China.
First Affiliated Hospital of GuangXi Medical University · CNGuangxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this study was to investigate the relationship between left atrial (LA) myocardial function and left ventricular (LV) diastolic dysfunction in subjects with preserved LV ejection fraction (LVEF).

methodsThe study included a group of 118 hypertensive patients and normal subjects. LV diastolic dysfunction was classified into 4 groups: none, mild, moderate, and severe. Peak strain rates in systole (S-Sr), early diastole (E-Sr), and late diastole (A-Sr) were obtained from Doppler-derived strain rate imaging to evaluate LA myocardial deformation.

resultsNo significant difference in LA dimension was observed in subjects with different degrees of LV diastolic dysfunction, although LA myocardial strain rate parameters were all significantly different across the 4 groups (all with P < 0.001). Compared with patients of normal diastolic function, the mild diastolic dysfunction group had significantly lower E-Sr (0.62 ± 0.18 s⁻¹ vs 1.20 ± 0.38 s⁻¹, P < 0.001) and S-Sr (0.78 ± 0.16 s⁻¹ vs 0.94 ± 0.22 s⁻¹, P < 0.001) but increased A-Sr (1.14 ± 0.29 s⁻¹ vs 1.00 ± 0.23 s⁻¹, P = 0.05).

conclusionsBy using strain rate imaging, significant changes of LA deformation in response to different stages of LV diastolic dysfunction were detected in subjects with preserved LVEF. Quantification of LA myocardial function rather than LA size may have the potential to predict early LV diastolic dysfunction in subjects with preserved LVEF.

Indexed as

AdultAtrial Function, LeftDiastoleEchocardiography, DopplerFemaleFollow-Up StudiesHeart AtriaHumansMaleMiddle AgedMyocardial ContractionSeverity of Illness IndexSystoleVentricular Dysfunction, Left

Identifiers

PMID20960540
PMCPMC6653575
OpenAlexW2042887537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.