ArticleInternational urology and nephrology2011
A comparison of different methods for the determination of glomerular filtration rate in elderly patients with chronic renal failure.
Article in International urology and nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Pooled it
- Multiparametric ultrasound in the evaluation of kidney disease in elderly.Journal of ultrasound · 2020Review
- Assessment of glomerular filtration rate in elderly patients with chronic kidney disease.International urology and nephrology · 2013Article
- A correlation between acute kidney injury and myonecrosis after scheduled percutaneous coronary intervention.Journal of Zhejiang University. Science. B · 2013Observational
- Are cystatin C-based equations superior to creatinine-based equations for estimating GFR in Chinese elderly population?International urology and nephrology · 2012Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of the present study was to asses the accuracy of prediction equations in elderly patients with advanced renal disease (ARD). PATIENTS AND
methodsTwenty-three elderly patients (>60 years) with chronic kidney disease (CKD) stages 3-5 underwent technetium-99 m-diethylenetriaminepentaacetic acid (Tc-99m-DTPA) radionuclide measurement of glomerular filtration rate (GFR). To predict GFR, estimation formulas [Cockcroft-Gault (CG), 6-variable Modification of Diet in Renal Disease (6-var-MDRD) and the corrected 24-hour creatinine clearance (24-h CCL) method] were used. Estimates of bias and precision were obtained to compare prediction equations of GFR with standard radionuclide measurement.
resultsIn the present study, all the prediction equations overestimated the GFR measured with the radionuclide method. Six-var-MDRD and 24-h CCL methods correlated better with standard radionuclide measurements compared to the CG formula (Rc of 0.53 and 0.50 vs. 0.41, respectively) as for GFR prediction, but they were still insufficiently accurate.
conclusionGlomerular filtration rate prediction equations correlate poorly with standard radionuclide measurements and their use may lead to late initialization of renal replacement therapy in elderly patients with ARD. Therefore, measurement by standard radionuclide method (Tc-99m-DTPA) is recommended to accurately assess GFR in elderly patients with ARD.
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