PYHIN proteins: center stage in DNA sensing.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

23 citing papers in PubMed.

1. Multifaceted activation of STING axis upon Nipah and measles virus-induced syncytia formation.PLoS pathogens · 2024
   Article
2. Interplay between RNA viruses and cGAS/STING axis in innate immunity.Frontiers in cellular and infection microbiology · 2023
   Review
3. When STING Meets Viruses: Sensing, Trafficking and Response.Frontiers in immunology · 2020
   Review
4. The Trinity of cGAS, TLR9, and ALRs Guardians of the Cellular Galaxy Against Host-Derived Self-DNA.Frontiers in immunology · 2020
   Review
5. RalB degradation by dihydroartemisinin induces autophagy and IFI16/caspase-1 inflammasome depression in the human laryngeal squamous cell carcinoma.Chinese medicine · 2020
   Article
6. PYHIN Proteins and HPV: Role in the Pathogenesis of Head and Neck Squamous Cell Carcinoma.Microorganisms · 2019
   Review
7. PYHIN genes as potential biomarkers for prognosis of human papillomavirus-positive or -negative head and neck squamous cell carcinomas.Molecular biology reports · 2019
   Article
8. C-Terminal Domain of Hemocyanin, a Major Antimicrobial Protein fromFrontiers in immunology · 2017
   Article
9. The Enemy within: Innate Surveillance-Mediated Cell Death, the Common Mechanism of Neurodegenerative Disease.Frontiers in neuroscience · 2016
   Article
10. The Nuclear DNA Sensor IFI16 Acts as a Restriction Factor for Human Papillomavirus Replication through Epigenetic Modifications of the Viral Promoters.Journal of virology · 2015
    Article
11. Herpes simplex virus-1 infection or Simian virus 40-mediated immortalization of corneal cells causes permanent translocation of NLRP3 to the nuclei.International journal of ophthalmology · 2015
    Article
12. IFI16 Expression Is Related to Selected Transcription Factors during B-Cell Differentiation.Journal of immunology research · 2015
    Article
13. Pattern recognition receptors and central nervous system repair.Experimental neurology · 2014
    Review
14. Innate immune response after adenoviral gene delivery into skin is mediated by AIM2, NALP3, DAI and mda5.SpringerPlus · 2013
    Article
15. Immune sensing of DNA.Immunity · 2013
    Review
16. DNA-dependent activator of interferon-regulatory factors (DAI) promotes lupus nephritis by activating the calcium pathway.The Journal of biological chemistry · 2013
    Article
17. Genome-wide association study for levels of total serum IgE identifies HLA-C in a Japanese population.PloS one · 2013
    Article
18. RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication.PLoS pathogens · 2013
    Article
19. Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.Immunity · 2012
    Article
20. The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication.PLoS pathogens · 2012
    Article

Corrections and comments

• Comment on
  IFI16 is an innate immune sensor for intracellular DNA.2010

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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