Evidence map›Paper›PMID 20959798›Full record

ArticleNature immunology2010

A model for harmonizing flow cytometry in clinical trials.

Holden T Maecker, J Philip McCoy, FOCIS Human Immunophenotyping Consortium, Michael Amos, John Elliott, Adolfas Gaigalas, Lili Wang, Richard Aranda, Jacques Banchereau, Chris Boshoff and 35 more

Erratum issuedAbstract read
In one paragraph

Article in Nature immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed.

  1. Trial
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  7. Review
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  17. Article
  18. A roadmap for translational cancer glycoimmunology at single cell resolution.Journal of experimental & clinical cancer research : CR · 2022
    Review
  19. Article
  20. Review

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
    DiMeglio, Paola [corrected to Di Meglio, Paola]; Nestle, Frank [corrected to Nestle, Frank O]; Villnova, Federica [corrected to Villanova, Federica]
  • Erratum issued
5 · Who and what money

Authors and funding

45 authors.

Holden T MaeckerInstitute for Immunity, Transplantation and Infection, Stanford University, Stanford, California, USA. maecker@stanford.edu
J Philip McCoy
FOCIS Human Immunophenotyping Consortium
Michael Amos
John Elliott
Adolfas Gaigalas
Lili Wang
Richard Aranda
Jacques Banchereau
Chris Boshoff
Jonathan Braun
Yael Korin
Elaine Reed
Judy Cho
David Hafler
Mark Davis
C Garrison Fathman
William Robinson
Thomas Denny
Kent Weinhold
Bela Desai
Betty Diamond
Peter Gregersen
Paola Di Meglio
Paola DiMeglio
Frank O Nestle
Frank Nestle
Mark Peakman
Federica Villanova
Federica Villnova
John Ferbas
Elizabeth Field
Aaron Kantor
Thomas Kawabata
Wendy Komocsar
Michael Lotze
Jerry Nepom
Hans Ochs
Raegan O'Lone
Deborah Phippard
Scott Plevy
Stephen Rich
Mario Roederer
Dan Rotrosen
Jung-Hua Yeh

Funding

Flow Cytometry Core FacilityZICHL005905 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI DAGUR, PRADEEP · 2009 to 2025
$32.3M
Intramural NIH HHS Z99 HL999999Intramural NIH HHS ZIC HL005905
6 · The paper itself

Abstract

Complexities in sample handling, instrument setup and data analysis are barriers to the effective use of flow cytometry to monitor immunological parameters in clinical trials. The novel use of a central laboratory may help mitigate these issues.

Indexed as

Clinical Trials as TopicFlow CytometryHumansSpecimen Handling

Identifiers

PMID20959798
PMCPMC3400260

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.