Evidence map›Paper›PMID 20959161›Full record

ReviewCurrent topics in developmental biology2010

Retinal determination the beginning of eye development.

Justin P Kumar

Open access · bronzeAbstract readReview
In one paragraph

Review in Current topics in developmental biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
10.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 85 citations in OpenAlex.

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  15. Patterning of theFrontiers in cell and developmental biology · 2023
    Review
  16. Article
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  19. The Role of microRNAs in theFrontiers in cell and developmental biology · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Justin P KumarDepartment of Biology, Indiana University, Bloomington, Indiana, USA.
Indiana University Bloomington · US

Funding

Function of the Six and Eya Genes in Retinal DevelopmentR56EY014863 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI KUMAR, JUSTIN P · 2009 to 2009
$381k
NEI NIH HHS R56 EY014863
6 · The paper itself

Abstract

The road to producing an eye begins with the decision to commit a population of cells to adopting an eye tissue fate, the process of retinal determination. Over the past decade and a half, a network of transcription factors has been found to mediate this process in all seeing animals. This retinal determination network is known to regulate not only tissue fate but also cell proliferation, pattern formation, compartment boundary establishment, and even retinal cell specification. The compound eye of the fruit fly, Drosophila melanogaster, has proven to be an excellent experimental system to study the mechanisms by which this network regulates organogenesis and tissue patterning. In fact the founding members of most of the gene families that make up this network were first isolated in Drosophila based on loss-of-function phenotypes that affect the eye. This chapter will highlight the history of discovery of the retinal determination network and will draw attention to the molecular and biochemical mechanisms that underlie our understanding of how the fate of the retina is determined.

Indexed as

Drosophila melanogasterAnimalsDrosophila ProteinsEye ProteinsGene Expression Regulation, DevelopmentalOrganogenesisPhotoreceptor Cells, InvertebrateRetinaDrosophila ProteinsEye Proteins

Identifiers

PMID20959161
PMCPMC5830122
OpenAlexW2190291318

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.