Evidence map›Paper›PMID 20959022›Full record

ReviewGenome biology2010

Capturing the dynamic epigenome.

Roger B Deal, Steven Henikoff

Abstract readComparative StudyReview
In one paragraph

Review in Genome biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Roger B DealBasic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Steven Henikoff

Funding

Genome-wide measurement of histone replacement rates: a new dimension in epigenomR21DA025758 · NIDA · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HENIKOFF, STEVEN · 2008 to 2009
$704k
A new epigenome profiling method for the study of cell fate specificationF32GM083449 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DEAL, ROGER BANCROFT · 2008 to 2010
$149k
Howard Hughes Medical InstituteNIDA NIH HHS 1R21DA025758NIGMS NIH HHS 1F32GM083449NIGMS NIH HHS F32 GM083449
6 · The paper itself

Abstract

Traditional methods for epigenomic analysis provide a static picture of chromatin, which is actually a highly dynamic assemblage. Recent approaches have allowed direct measurements of chromatin dynamics, providing deeper insights into processes such as transcription, DNA replication and epigenetic inheritance.

Indexed as

Epigenesis, GeneticChromatinDNA MethylationDNA ReplicationEpigenomicsFluorescence Recovery After PhotobleachingHistonesSequence Analysis, DNATranscription FactorsTransgenesChromatinHistonesTranscription Factors

Identifiers

PMID20959022
PMCPMC3218653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.