Evidence map›Paper›PMID 20956242›Full record

ArticleBioinformatics (Oxford, England)2010

FILTREST3D: discrimination of structural models using restraints from experimental data.

Michal J Gajda, Irina Tuszynska, Marta Kaczor, Anastasia Yu Bakulina, Janusz M Bujnicki

Open access · bronzeAbstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michal J GajdaInternational Institute of Molecular and Cell Biology, ul. Ks. Trojdena 4, Warsaw, Poland.
Irina Tuszynska
Marta Kaczor
Anastasia Yu Bakulina
Janusz M Bujnicki
International Institute of Molecular and Cell Biology · PL

Funding

High-Accuracy Protein Models Derived from Lower Resolution DataR01GM081680 · NIGMS · IOWA STATE UNIVERSITY · PI KLOCZKOWSKI, ANDRZEJ · 2007 to 2009
$763k
NIGMS NIH HHS R01 GM081680NIGMS NIH HHS R01-GM081680
6 · The paper itself

Abstract

summaryAutomatic methods for macromolecular structure prediction (fold recognition, de novo folding and docking programs) produce large sets of alternative models. These large model sets often include many native-like structures, which are often scored as false positives. Such native-like models can be more easily identified based on data from experimental analyses used as structural restraints (e.g. identification of nearby residues by cross-linking, chemical modification, site-directed mutagenesis, deuterium exchange coupled with mass spectrometry, etc.). We present a simple server for scoring and ranking of models according to their agreement with user-defined restraints. AVAILABILITY: FILTREST3D is freely available for users as a web server and standalone software at: http://filtrest3d.genesilico.pl/ CONTACT: iamb@genesilico.pl SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Indexed as

Models, MolecularNucleic Acid ConformationProtein ConformationSoftwareComputational Biology

Identifiers

PMID20956242
PMCPMC2982159
OpenAlexW2125042228

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.