ReviewNeuron2010
Neurocognitive phenotypes and genetic dissection of disorders of brain and behavior.
Review in Neuron, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Genetic fingerprinting with heritable phenotypes of the resting-state brain network topology.Communications biology · 2024Article
- Assessing inter-individual differences with task-related functional neuroimaging.Nature human behaviour · 2019Review
- Behavioral and Psychological Phenotyping of Physical Activity and Sedentary Behavior: Implications for Weight Management.Obesity (Silver Spring, Md.) · 2017Review
- Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders.Nature reviews. Genetics · 2015Review
- Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.PLoS genetics · 2014Article
- The NIMH Research Domain Criteria (RDoC) Project: implications for genetics research.Mammalian genome : official journal of the International Mammalian Genome Society · 2014Review
- Genes encoding heterotrimeric G-proteins are associated with gray matter volume variations in the medial frontal cortex.Cerebral cortex (New York, N.Y. : 1991) · 2013Article
- Aberrant sodium channel activity in the complex seizure disorder of Celf4 mutant mice.The Journal of physiology · 2013Article
- The young and the reckless.Nature neuroscience · 2012Article
- Discovering relations between mind, brain, and mental disorders using topic mapping.PLoS computational biology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Elucidating the molecular mechanisms underlying quantitative neurocognitive phenotypes will further our understanding of the brain's structural and functional architecture and advance the diagnosis and treatment of the psychiatric disorders that these traits underlie. Although many neurocognitive traits are highly heritable, little progress has been made in identifying genetic variants unequivocally associated with these phenotypes. A major obstacle to such progress is the difficulty in identifying heritable neurocognitive measures that are precisely defined and systematically assessed and represent unambiguous mental constructs, yet are also amenable to the high-throughput phenotyping necessary to obtain adequate power for genetic association studies. In this perspective we compare the current status of genetic investigations of neurocognitive phenotypes to that of other categories of biomedically relevant traits and suggest strategies for genetically dissecting traits that may underlie disorders of brain and behavior.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.