ArticleNeuron2010
Neurogenetics: advancing the "next-generation" of brain research.
Article in Neuron, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Use of next generation sequencing technologies in research and beyond: are participants with mental health disorders fully protected?BMC medical ethics · 2012Pooled it
- Oxidative stress in Rett syndrome: natural history, genotype, and variants.Redox report : communications in free radical research · 2011Trial
- GABAergic neuronal dysfunction underlies tremor in spinocerebellar ataxia 3.Disease models & mechanisms · 2025Article
- Regulatory roles of eugenol in paraquat-altered SNCA/LZTS3/MAPT in the cerebellum of Wistar rats.Laboratory animal research · 2025Article
- Advances in the discovery and analyses of human tandem repeats.Emerging topics in life sciences · 2023Review
- Clinical and molecular findings in a Turkish family with an ultra-rare condition, ELP2-related neurodevelopmental disorder.Molecular biology reports · 2021Article
- Sleep as a translationally-relevant endpoint in studies of autism spectrum disorder (ASD).Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Review
- Modeling and Predicting Developmental Trajectories of Neuropsychiatric Dimensions Associated With Copy Number Variations.The international journal of neuropsychopharmacology · 2019Review
- Fully automated leg tracking of Drosophila neurodegeneration models reveals distinct conserved movement signatures.PLoS biology · 2019Article
- Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain.Neural plasticity · 2018Article
- Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanisms.Nature communications · 2016Article
- CHRNA7 triplication associated with cognitive impairment and neuropsychiatric phenotypes in a three-generation pedigree.European journal of human genetics : EJHG · 2014Article
- Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease.Nature medicine · 2014Article
- SHC2 gene copy number in multiple system atrophy (MSA).Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2014Article
- Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis.The FEBS journal · 2013Review
- Differential gene body methylation and reduced expression of cell adhesion and neurotransmitter receptor genes in adverse maternal environment.Translational psychiatry · 2013Article
- Nutrient-dependent/pheromone-controlled adaptive evolution: a model.Socioaffective neuroscience & psychology · 2013Review
- Drosophila as a model to study mitochondrial dysfunction in Parkinson's disease.Cold Spring Harbor perspectives in medicine · 2012Review
- Single cell genomics of the brain: focus on neuronal diversity and neuropsychiatric diseases.Current genomics · 2012Article
- Exome sequencing as a diagnostic tool in a case of undiagnosed juvenile-onset GM1-gangliosidosis.Neurology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
There can be little doubt that genetics has transformed our understanding of mechanisms mediating brain disorders. The last two decades have brought tremendous progress in terms of accurate molecular diagnoses and knowledge of the genes and pathways that are involved in a large number of neurological and psychiatric disorders. Likewise, new methods and analytical approaches, including genome array studies and "next-generation" sequencing technologies, are bringing us deeper insights into the subtle complexities of the genetic architecture that determines our risks for these disorders. As we now seek to translate these discoveries back to clinical applications, a major challenge for the field will be in bridging the gap between genes and biology. In this Overview of Neuron's special review issue on neurogenetics, we reflect on progress made over the last two decades and highlight the challenges as well as the exciting opportunities for the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.