Evidence map›Paper›PMID 20954963›Full record

SynthesisJournal of alternative and complementary medicine (New York, N.Y.)2010

Auriculotherapy for pain management: a systematic review and meta-analysis of randomized controlled trials.

Gary N Asher, Daniel E Jonas, Remy R Coeytaux, Aimee C Reilly, Yen L Loh, Alison A Motsinger-Reif, Stacey J Winham

4 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of alternative and complementary medicine (New York, N.Y.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 60 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02367729 nacompletednot on this mapstarted 2015, after this paper: background citation

Efficacy of Auricular Neurostimulation for Adolescents With Pain-Associated Functional Gastrointestinal Disorders

TypeinterventionalSponsorMedical College of WisconsinRan2015 to 2017Enrolled115ConditionsFunctional Disorder of Intestine, Nausea PersistentArmsNeurostimulator, Sham
NCT02540512 early_phase1withdrawnnot on this mapstarted 2017, after this paper: background citation

Auricular Acupuncture for the Acute Management of Pain in the Emergency Department

TypeinterventionalSponsorLoma Linda UniversityRan2017 to 2017Enrolled0ConditionsMusculoskeletal Pain, PainArmsAuricular Acupuncture, Acupuncture, Placebo Acupuncture, hydrocodone / acetaminophen 5mg/325mg, Placebo Pill
NCT03860259 nacompletednot on this mapstarted 2020, after this paper: background citation

The Effect of Auriculotherapy for Post-Operative Pain Management Following Rotator Cuff Surgery: A Randomized, Placebo-Controlled Study

TypeinterventionalSponsorJacques E. ChellyRan2020 to 2021Enrolled50ConditionsAcute Pain, Surgery, Shoulder PainArmsAuriculotherapy cryopuncture device without nitrogen gas, Auriculotherapy cryopuncture device with nitrogen gas
NCT04920097 nacompletednot on this mapstarted 2021, after this paper: background citation

Auricular Point Acupressure to Manage Chemotherapy Induced Neuropathy

TypeinterventionalSponsorThe University of Texas Health Science Center, HoustonRan2021 to 2026Enrolled238ConditionsChemotherapy-induced NeuropathyArmsIn-person training for seed placement and APA, Virtual training for seed placement and APA, Usual Care, Post-training zoom session for seed placement and APA coaching
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gary N AsherDepartment of Family Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. gasher@med.unc.edu
Daniel E Jonas
Remy R Coeytaux
Aimee C Reilly
Yen L Loh
Alison A Motsinger-Reif
Stacey J Winham

Funding

UNC Research Fellowship in Complementary and Alternative MedicineT32AT003378 · NCCIH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Keturah Ruth Faurot, Susan Gaylord · 2007 to 2026
$7.8M
Biostatistics Training in the Omics EraT32GM081057 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI MUSE, SPENCER V. · 2007 to 2019
$2.5M
NCCIH NIH HHS T32AT003378NIGMS NIH HHS T32GM081057
6 · The paper itself

Abstract

objectivesSide-effects of standard pain medications can limit their use. Therefore, nonpharmacologic pain relief techniques such as auriculotherapy may play an important role in pain management. Our aim was to conduct a systematic review and meta-analysis of studies evaluating auriculotherapy for pain management.

designMEDLINE,(®) ISI Web of Science, CINAHL, AMED, and Cochrane Library were searched through December 2008. Randomized trials comparing auriculotherapy to sham, placebo, or standard-of-care control were included that measured outcomes of pain or medication use and were published in English. Two (2) reviewers independently assessed trial eligibility, quality, and abstracted data to a standardized form. Standardized mean differences (SMD) were calculated for studies using a pain score or analgesic requirement as a primary outcome.

resultsSeventeen (17) studies met inclusion criteria (8 perioperative, 4 acute, and 5 chronic pain). Auriculotherapy was superior to controls for studies evaluating pain intensity (SMD, 1.56 [95% confidence interval (CI): 0.85, 2.26]; 8 studies). For perioperative pain, auriculotherapy reduced analgesic use (SMD, 0.54 [95% CI: 0.30, 0.77]; 5 studies). For acute pain and chronic pain, auriculotherapy reduced pain intensity (SMD for acute pain, 1.35 [95% CI: 0.08, 2.64], 2 studies; SMD for chronic pain, 1.84 [95% CI: 0.60, 3.07], 5 studies). Removal of poor quality studies did not alter the conclusions. Significant heterogeneity existed among studies of acute and chronic pain, but not perioperative pain.

conclusionsAuriculotherapy may be effective for the treatment of a variety of types of pain, especially postoperative pain. However, a more accurate estimate of the effect will require further large, well-designed trials.

Indexed as

Acupuncture, EarAnalgesiaPain ManagementHumansPain MeasurementPerioperative PeriodRandomized Controlled Trials as Topic

Identifiers

PMID20954963
PMCPMC3110838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.