ReviewDialogues in clinical neuroscience2010
Genetics in schizophrenia: where are we and what next?
Review in Dialogues in clinical neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 60 citations in OpenAlex.
- Influence of ANKK1 and DRD2 polymorphisms in response to haloperidol.European archives of psychiatry and clinical neuroscience · 2013Trial
- Implications of SNP-triggered miRNA dysregulation in Schizophrenia development.Frontiers in genetics · 2024Review
- Characterizing the Shared Genetic Underpinnings of Schizophrenia and Cardiovascular Disease Risk Factors.The American journal of psychiatry · 2023Article
- Altered offspring neurodevelopment in an L-NAME-induced preeclampsia rat model.Frontiers in pediatrics · 2023Article
- Neuroimaging in schizophrenia: A review article.Frontiers in neuroscience · 2022Review
- Microvascular anomaly conditions in psychiatric disease. Schizophrenia - angiogenesis connection.Neuroscience and biobehavioral reviews · 2017Review
- Role of calcium channels in bipolar disorder.Current psychopharmacology · 2017Article
- A comparative study of disease genes and drug targets in the human protein interactome.BMC bioinformatics · 2015Article
- Theory of Mind in Bipolar Disorder, with Comparison to the Impairments Observed in Schizophrenia.Frontiers in psychiatry · 2015Review
- NMDA receptor and schizophrenia: a brief history.Schizophrenia bulletin · 2012Article
- Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012Article
- Genetic variations in the ADAMTS12 gene are associated with schizophrenia in Puerto Rican patients of Spanish descent.Neuromolecular medicine · 2012Article
- AKT/GSK3 signaling pathway and schizophrenia.Frontiers in molecular neuroscience · 2012Article
- Dissecting the Syndrome of Schizophrenia: Progress toward Clinically Useful Biomarkers.Schizophrenia research and treatment · 2011Article
- Epigenetic profile of the immune system associated with symptom severity and treatment response in schizophrenia.Journal of psychiatry & neuroscience : JPNArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding the genetic basis of schizophrenia continues to be major challenge. The research done during the last two decades has provided several candidate genes which unfortunately have not been consistently replicated across or within a population. The recent genome-wide association studies (GWAS) and copy number variation (CNV) studies have provided important evidence suggesting a role of both common and rare large CNVs in schizophrenia genesis. The burden of rare copy number variations appears to be increased in schizophrenia patients. A consistent observation among the GWAS studies is the association with schizophrenia of genetic markers in the major histocompatibility complex (6p22.1)-containing genes including NOTCH4 and histone protein loci. Molecular genetic studies are also demonstrating that there is more overlap between the susceptibility genes for schizophrenia and bipolar disorder than previously suspected. In this review we summarize the major findings of the past decade and suggest areas of future research.
Indexed as
Identifiers
20954426PMC3181975W101570666What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.