ArticleInternational urology and nephrology2011
Two icodextrin exchanges per day in peritoneal dialysis patients with ultrafiltration failure: one center's experience and review of the literature.
Article in International urology and nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Use of 2 Icodextrin Exchanges per Day in Incident Peritoneal Dialysis Patients: Are There Incremental Benefits?Kidney international reports · 2025Article
- The Double-Icodextrin Dose Randomized Controlled Trial of a Double Icodextrin Dose for Older Patients on Incremental Continuous Ambulatory Peritoneal Dialysis.Kidney international reports · 2025Article
- Glycemic Control in Patients with Diabetes on Peritoneal Dialysis: From Glucose Sparing Approach to Glucose Monitoring.Life (Basel, Switzerland) · 2025Review
- Article
- Icodextrin-associated generalized exfoliative skin rash in a CAPD patient: a case-report.BMC nephrology · 2018Article
- Icodextrin and peritoneal dialysis: advantages and new applications.International urology and nephrology · 2018Review
- [Peritoneal dialysis from the beginnings up to today: which developments of the last decades were important?].Wiener medizinische Wochenschrift (1946) · 2013Review
- Bimodal solutions or twice-daily icodextrin to enhance ultrafiltration in peritoneal dialysis patients.International journal of nephrology · 2013Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAt present, only one exchange of an icodextrin-based solution is recommended to increase peritoneal ultrafiltration (UF) during long-dwell exchanges in peritoneal dialysis (PD) patients with impaired UF.
aimTo review our experience with two icodextrin exchanges per day on net UF and body weight in PD patients with poor UF.
methodsData were analyzed on nine patients with poor UF on chronic PD who were given two icodextrin exchanges per day for 6 months and had various clinical and biochemical parameters assessed monthly.
resultsAdministration of icodextrin twice daily reduced the body weight in six of nine patients by an average of 2.9 ± 1.2 kg, a reduction that was maintained throughout the study; two patients gained 0.5 kg; and, in one patient, the measurements were inadequate. Mean blood pressure was reduced. Mean serum creatinine increased slightly. Serum sodium levels decreased from a mean baseline level of 134 ± 3 to 132 ± 4 mmol/L at three and six months. Among the diabetics in this group, average daily insulin requirements were 44 ± 35 units/day at baseline and 40 ± 23 units/day after 6 months. Hb1Ac levels remained stable throughout the study period.
conclusionThe use of two icodextrin exchanges per day reduced body weight in six of the nine patients and appeared to be safe. Long-term prospective studies are needed to assess the contribution of twice-daily icodextrin to the management of peritoneal dialysis patients with ultrafiltration failure and its long-term safety.
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