ReviewMolecules (Basel, Switzerland)2010
Role of oxidant scavengers in the prevention of Ca²+ homeostasis disorders.
Review in Molecules (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed, 25 citations in OpenAlex.
- Modulatory Impact of Oxidative Stress on Action Potentials in Pathophysiological States: A Comprehensive Review.Antioxidants (Basel, Switzerland) · 2024Review
- Role of calcium-sensing receptor in regulating activation susceptibility of postovulatory aging mouse oocytes.The Journal of reproduction and development · 2023Article
- Hydrogen peroxide attenuates refilling of intracellular calcium store in mouse pancreatic acinar cells.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2017Article
- Calcium Dynamics of Ex Vivo Long-Term Cultured CD8+ T Cells Are Regulated by Changes in Redox Metabolism.PloS one · 2016Article
- Modeling Local X-ROS and Calcium Signaling in the Heart.Biophysical journal · 2015Article
- Amyloid-beta disrupts calcium and redox homeostasis in brain endothelial cells.Molecular neurobiology · 2015Article
- Peripheral arterial calcification: prevalence, mechanism, detection, and clinical implications.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2014Review
- Role of Na+/Ca2+ exchanger (NCX) in modulating postovulatory aging of mouse and rat oocytes.PloS one · 2014Article
- Redox control of the senescence regulator interleukin-1α and the secretory phenotype.The Journal of biological chemistry · 2013Article
- Redox-control of the alarmin, Interleukin-1α.Redox biology · 2013Article
- α-lipoic acid reduces hypertension and increases baroreflex sensitivity in renovascular hypertensive rats.Molecules (Basel, Switzerland) · 2012Article
- SFE-CO2 extract from Typhonium giganteum Engl. tubers, induces apoptosis in human hepatoma SMMC-7721 cells involvement of a ROS-mediated mitochondrial pathway.Molecules (Basel, Switzerland) · 2011Article
- Lanthanum chloride suppresses oxysterol-induced ECV-304 cell apoptosis via inhibition of intracellular Ca(2+) concentration elevation, oxidative stress, and activation of ERK and NF-κB signaling pathways.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2011Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A number of disorders, such as Alzheimer disease and diabetes mellitus, have in common the alteration of the redox balance, resulting in an increase in reactive oxygen species (ROS) generation that might lead to the development of apoptosis and cell death. It has long been known that ROS can significantly alter Ca²+ mobilization, an intracellular signal that is involved in the regulation of a wide variety of cellular functions. Cells have a limited capability to counteract the effects of oxidative stress, but evidence has been provided supporting the beneficial effects of exogenous ROS scavengers. Here, we review the effects of oxidative stress on intracellular Ca²+ homeostasis and the role of antioxidants in the prevention and treatment of disorders associated to abnormal Ca²+ mobilization induced by ROS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.