Evidence map›Paper›PMID 20952243›Full record

ArticleParkinsonism & related disorders2011

Measurement of patient-centered outcomes in Parkinson's disease: what do patients really want from their treatment?

Anne N Nisenzon, Michael E Robinson, Dawn Bowers, Evangelia Banou, Irene Malaty, Michael S Okun

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Parkinsonism & related disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Measurement of patients' acceptable symptom levels and priorities for symptom improvement in advanced prostate cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Measurement of patients' acceptable symptom levels and priorities for symptom improvement in advanced lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anne N NisenzonDepartment of Clinical and Health Psychology, University of Florida, Health Science Center, P.O. Box 100165, Gainesville, FL 32610-0165, USA. nisenzon@phhp.ufl.edu
Michael E Robinson
Dawn Bowers
Evangelia Banou
Irene Malaty
Michael S Okun

Funding

Masked Faces in Parkinson Disease: Mechanism &TreatmentR01NS050633 · NINDS · UNIVERSITY OF FLORIDA · PI BOWERS, DAWN · 2005 to 2008
$1.3M
Pain Rehabilitation: Patient Centered OutcomesR01NR010324 · NINR · UNIVERSITY OF FLORIDA · PI ROBINSON, MICHAEL E · 2006 to 2008
$666k
NINDS NIH HHS R01 NS047119NINDS NIH HHS R01 NS050633NINR NIH HHS R01 NR010324
6 · The paper itself

Abstract

backgroundParkinson's disease (PD) impacts several domains of functioning, some of which may be neglected when designing treatment or evaluating outcome using current clinical standards. We therefore argue that taking the patients' perspectives of their condition may allow for a more in-depth assessment of patient goals and subsequent tailoring of care.

methodsOne hundred and forty-eight patients with idiopathic PD completed a modified version of the Patient-Centered Outcomes Questionnaire (PCOQ-PD), to evaluate treatment success and expectations from the patient's perspective across 10 motor and non-motor functional domains. We also examined patient subgroups based on importance of improvement in various domains.

resultsPatients' ratings suggested there was substantial variation in functional interference that was generally unrelated to demographic variables. On average, across all domains, patients indicated a 50.32% reduction in symptoms would be successful (range = 40.63-58.23%), regardless of treatment experience. Change scores between patients' usual levels of symptom interference and their treatment success levels suggested a greater degree of change was desired in motor versus non-motor domains (p < 0.05). Finally, cluster analyses revealed two patient subgroups based on overall importance of improvement (High vs. Low Importance Endorsement). Notably, the two groups differed in self-reported usual symptom levels despite having similar clinical severity.

conclusionsWe empirically examined treatment success from the PD patient's view as opposed to clinician judgment alone, thereby broadening the set of criteria by which to evaluate outcome. Findings from this exploratory study may guide future treatment emphases and guide patient-provider communication via clarification of patient-defined success.

Indexed as

Patient SatisfactionSurveys and QuestionnairesAgedFemaleHumansMaleMiddle AgedParkinson DiseasePatient-Centered CareTreatment Outcome

Identifiers

PMID20952243
PMCPMC3034811

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.