ArticleBrain research2011
Characterization of voltage-activated ionic currents in the GnRH-containing terminalis nerve in transgenic zebrafish.
Article in Brain research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Sensory Integration: Cross-Modal Communication Between the Olfactory and Visual Systems in Zebrafish.Chemical senses · 2019Review
- GnRH-mediated olfactory and visual inputs promote mating-like behaviors in male zebrafish.PloS one · 2017Article
- Neurobiological study of fish brains gives insights into the nature of gonadotropin-releasing hormone 1-3 neurons.Frontiers in endocrinology · 2013Review
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
The terminalis nerve (TN) is in a class of cranial nerves that plays important roles in animal development, physiology and behavior. Here, we report a study on the characterization of voltage-activated ionic currents in GnRH-containing TN cells in zebrafish. The experiments were performed using acutely dissociated TN cells from the transgenic zebrafish Tg (GnRH-3::GFP). In the transgenic zebrafish, the TN cells express GFP under the transcriptional control of the zebrafish GnRH-3 promoter. In all of the GnRH-containing TN cells examined, we recorded both low-voltage-activated (LVA) and high-voltage-activated (HVA) calcium current (I(Ca)). The characteristics of the I(Ca) were similar to those described in other zebrafish cell types. However, the distribution patterns of the currents in the GnRH-containing TN cells were different in comparison to the distribution of the currents in other cell types. In addition, we characterized TTX-sensitive sodium current (I(Na)) and 4AP-sensitive and TEA-resistant potassium current (I(K)). The characteristics of voltage-activated I(Na) and I(K) in the GnRH-containing TN cells were similar to those described in other zebrafish cell types. Together, the data from this study revealed the electrophysiological properties of the GnRH-containing TN cells, thereby providing insight on the regulatory mechanisms of TN-signaling in animal physiology.
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