ReviewBiochimica et biophysica acta2011
Mitochondrial involvement in cell death of non-mammalian eukaryotes.
Review in Biochimica et biophysica acta, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed.
- MicroRNA-34-5p regulates the expression of ecdysteroid receptor (ECR) in the process of salivary gland degeneration of ticks.Parasites & vectors · 2025Article
- Transcriptome reveals the roles and potential mechanisms of CeRNA in the regulation of salivary gland development in the tickFrontiers in cellular and infection microbiology · 2025Article
- Synthesis and Anticancer Evaluation of Novel 7-Aza-Coumarine-3-Carboxamides.International journal of molecular sciences · 2023Article
- Sayonara to some evolutionary puzzles in the Bcl-2 family.The EMBO journal · 2023Article
- Synthesis, Self-Assembly in Crystalline Phase and Anti-Tumor Activity of 2-(2-/4-Hydroxybenzylidene)thiazolo[3,2-Molecules (Basel, Switzerland) · 2022Article
- Identification of the Bcl-2 and Bax homologs from Rhipicephalus haemaphysaloides and their function in the degeneration of tick salivary glands.Parasites & vectors · 2021Article
- Infection ofFrontiers in physiology · 2021Article
- Human cultured IMR-32 neuronal-like and U87 glial-like cells have different patterns of toxicity under fluoride exposure.PloS one · 2021Article
- The role of mitochondrial fusion and fission in the process of cardiac oxidative stress.Histology and histopathology · 2020Review
- Study of Guanxinning Injection on Regulatory Mechanism of Bcl-2 and Bax by Liquid Nitrogen Freezing-Mediated Femoral Head Necrosis.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- Endoplasmic reticulum (ER) stress triggers Hax1-dependent mitochondrial apoptotic events in cardiac cells.Apoptosis : an international journal on programmed cell death · 2016Article
- Loss of Drosophila i-AAA protease, dYME1L, causes abnormal mitochondria and apoptotic degeneration.Cell death and differentiation · 2016Article
- Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model.Human molecular genetics · 2015Article
- Detecting apoptosis in Drosophila tissues and cells.Methods (San Diego, Calif.) · 2014Review
- Aging and cell death in the other yeasts, Schizosaccharomyces pombe and Candida albicans.FEMS yeast research · 2014Review
- Longevity pathways and memory aging.Frontiers in genetics · 2014Review
- Loss of dE2F compromises mitochondrial function.Developmental cell · 2013Article
- Oxidation of the yeast mitochondrial thioredoxin promotes cell death.Antioxidants & redox signaling · 2013Article
- Multiple functions of BCL-2 family proteins.Cold Spring Harbor perspectives in biology · 2013Review
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Although mitochondria are essential organelles for long-term survival of eukaryotic cells, recent discoveries in biochemistry and genetics have advanced our understanding of the requirements for mitochondria in cell death. Much of what we understand about cell death is based on the identification of conserved cell death genes in Drosophila melanogaster and Caenorhabditis elegans. However, the role of mitochondria in cell death in these models has been much less clear. Considering the active role that mitochondria play in apoptosis in mammalian cells, the mitochondrial contribution to cell death in non-mammalian systems has been an area of active investigation. In this article, we review the current research on this topic in three non-mammalian models, C. elegans, Drosophila, and Saccharomyces cerevisiae. In addition, we discuss how non-mammalian models have provided important insight into the mechanisms of human disease as they relate to the mitochondrial pathway of cell death. The unique perspective derived from each of these model systems provides a more complete understanding of mitochondria in programmed cell death. This article is part of a Special Issue entitled Mitochondria: the deadly organelle.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.