Evidence map›Paper›PMID 20950421›Full record

ArticleBMC public health2010

Increasing reports of non-tuberculous mycobacteria in England, Wales and Northern Ireland, 1995-2006.

Jonathan E Moore, Michelle E Kruijshaar, L Peter Ormerod, Francis Drobniewski, Ibrahim Abubakar

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 4 pooled it
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 4 syntheses or guidelines pooled it, 205 citations in OpenAlex.

  1. Pooled it
  2. Prevalence ofFrontiers in microbiology · 2024
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. Description and complete genome sequence ofFrontiers in microbiology · 2026
    Article
  8. DisseminatedFrontiers in immunology · 2026
    Review
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jonathan E MooreHealth Protection Agency Centre for Infections, Respiratory Diseases Department - Tuberculosis Section, 61 Colindale Avenue, London NW9 5EQ, UK. jonathan.moore@hpa.org.uk
Michelle E Kruijshaar
L Peter Ormerod
Francis Drobniewski
Ibrahim Abubakar
Public Health England · GBRoyal Blackburn Teaching Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-tuberculous mycobacteria have long been identified as capable of causing human disease and the number at risk, due to immune-suppression, is rising. Several reports have suggested incidence to be increasing, yet routine surveillance-based evidence is lacking. We investigated recent trends in, and the epidemiology of, non-tuberculous mycobacterial infections in England, Wales and Northern Ireland, 1995-2006.

methodsHospital laboratories voluntarily report non-tuberculous mycobacterial infections to the Health Protection Agency Centre for Infections. Details reported include age and sex of the patient, species, specimen type and source laboratory. All reports were analysed.

resultsThe rate of non-tuberculous mycobacteria reports rose from 0.9 per 100,000 population in 1995 to 2.9 per 100,000 in 2006 (1608 reports). Increases were mainly in pulmonary specimens and people aged 60+ years. The most commonly reported species was Mycobacterium avium-intracellulare (43%); M. malmoense and M. kansasii were also commonly reported. M. gordonae showed the biggest increase over the study period rising from one report in 1995 to 153 in 2006. Clinical information was rarely reported.

conclusionsThe number and rate of reports increased considerably between 1995 and 2006, primarily in older age groups and pulmonary specimens. Increases in some species are likely to be artefacts but real changes in more pathogenic species, some of which will require clinical care, should not be excluded. Enhanced surveillance is needed to understand the true epidemiology of these infections and their impact on human health.

Indexed as

Mandatory ReportingAdultFemaleHumansLaboratories, HospitalMaleMiddle AgedMycobacteriumMycobacterium InfectionsPopulation SurveillanceUnited Kingdom

Identifiers

PMID20950421
PMCPMC2964631
OpenAlexW2079641738

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.