ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2011
Metacarpal thickness, width, length and medullary diameter in children--reference curves from the First Zürich Longitudinal Study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Revisiting the radiographic assessment of osteoporosis-Osteopenia in children 0-2 years of age. A systematic review.PloS one · 2020Pooled it
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- Online software Boneureka assessing bone age based on metacarpal length in healthy children: proof-of-concept study.Pediatric radiology · 2023Article
- Cortical Bone Mass is Low in Boys with Klinefelter Syndrome and Improves with Oxandrolone.Journal of the Endocrine Society · 2021Article
- Plasticity in the growth of body segments in relation to height-for-age and maternal education in Guatemala.American journal of human biology : the official journal of the Human Biology Council · 2020Article
- A longitudinal comparison of appendicular bone growth and markers of strength through adolescence in a South African cohort using radiogrammetry and pQCT.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Article
- Prevalence of SHOX haploinsufficiency among short statured children.Pediatric research · 2017Article
- Reference values for digital X-ray radiogrammetry parameters in children and adolescents in comparison to estimates in patients with distal radius fractures.Journal of bone and mineral metabolism · 2016Article
- Sex difference in age and performance in elite Swiss freestyle swimmers competing from 50 m to 1,500 m.SpringerPlus · 2014Article
- Sex-related differences and age of peak performance in breaststroke versus freestyle swimming.BMC sports science, medicine & rehabilitation · 2013Article
- Comparison of radiogrammetrical metacarpal indices in children and reference data from the First Zurich Longitudinal Study.Pediatric radiology · 2012Article
- Women achieve peak freestyle swim speed at earlier ages than men.Open access journal of sports medicine · 2012Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
summaryMetacarpal thickness (T), width (W), length (L) and medullary diameter (M) were measured in 3,121 X-rays from 231 healthy Caucasian children aged 3 to 19 years and analysed for bone age, age, height, weight and gender-related characteristics, showing highly differentiated growth patterns with prepubertal dips. Reference data for the four metacarpal measures are presented.
introductionThe aim of the study was to create and explore a reference database for metacarpal T, W, L and M in children.
methodsThree thousand one hundred twenty-one left-hand X-rays (1,661 from boys) from 231 healthy Caucasian subjects (119 boys) aged 3 to 19 years were analysed by BoneXpert, a programme for automatic analysis of hand X-rays and bone age (BA; in years).
resultsIn boys, growth of T, W and L shows a prepubertal decrease from BA 7 to 13 and then accelerates again. In girls, the same is seen only for T starting from BA 8 to 11, whereas W and L grow at a declining rate. M shows steady growth until BA 10.5 in girls and BA 13.5 in boys and then grows smaller in both. W is greater in boys from BA 6 onwards, while L is greater in girls from BA 9 to 13 and T from BA 11 to 14. BA is reflected best by L until start of puberty and by T and L thereafter.
conclusionT, W, L and M show highly differentiated growth patterns. These reference data provide a basis for further research into skeletal development and the management of hormone therapies in children.
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