Evidence map›Paper›PMID 20949040›Full record

ArticlePloS one2010

Inside the outbreak of the 2009 influenza A (H1N1)v virus in Mexico.

Hector M Zepeda-Lopez, Lizbeth Perea-Araujo, Angel Miliar-García, Aarón Dominguez-López, Beatriz Xoconostle-Cázarez, Eleazar Lara-Padilla, Jorge A Ramírez Hernandez, Edgar Sevilla-Reyes, Maria Esther Orozco, Armando Ahued-Ortega and 3 more

Abstract read
In one paragraph

Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Uptake and effectiveness of facemask against respiratory infections at mass gatherings: a systematic review.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hector M Zepeda-LopezLaboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Distrito Federal, Mexico.
Lizbeth Perea-Araujo
Angel Miliar-García
Aarón Dominguez-López
Beatriz Xoconostle-Cázarez
Eleazar Lara-Padilla
Jorge A Ramírez Hernandez
Edgar Sevilla-Reyes
Maria Esther Orozco
Armando Ahued-Ortega
Ignacio Villaseñor-Ruiz
Ricardo J Garcia-Cavazos
Luis M Teran

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza viruses pose a threat to human health because of their potential to cause global disease. Between mid March and mid April a pandemic influenza A virus emerged in Mexico. This report details 202 cases of infection of humans with the 2009 influenza A virus (H1N1)v which occurred in Mexico City as well as the spread of the virus throughout the entire country. METHODOLOGY AND

findingsFrom May 1st to May 5th nasopharyngeal swabs, derived from 751 patients, were collected at 220 outpatient clinics and 28 hospitals distributed throughout Mexico City. Analysis of samples using real time RT-PCR revealed that 202 patients out of the 751 subjects (26.9%) were confirmed to be infected with the new virus. All confirmed cases of human infection with the strain influenza (H1N1)v suffered respiratory symptoms. The greatest number of confirmed cases during the outbreak of the 2009 influenza A (H1N1)v were seen in neighbourhoods on the northeast side of Mexico City including Iztapalapa, Gustavo A. Madero, Iztacalco, and Tlahuac which are the most populated areas in Mexico City. Using these data, together with data reported by the Mexican Secretariat of Health (MSH) to date, we plot the course of influenza (H1N1)v activity throughout Mexico.

conclusionsOur data, which is backed up by MSH data, show that the greatest numbers of the 2009 influenza A (H1N1) cases were seen in the most populated areas. We speculate on conditions in Mexico which may have sparked this flu pandemic, the first in 41 years. We accept the hypothesis that high population density and a mass gathering which took in Iztapalapa contributed to the rapid spread of the disease which developed in three peaks of activity throughout the Country.

Indexed as

Disease OutbreaksHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanMexicoReverse Transcriptase Polymerase Chain Reaction

Identifiers

PMID20949040
PMCPMC2951908

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.