Evidence map›Paper›PMID 20948902›Full record

ReviewMarine drugs2010

N-acetylglucosamine: production and applications.

Jeen-Kuan Chen, Chia-Rui Shen, Chao-Lin Liu

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 386 citations in OpenAlex.

  1. Enhancing enzyme activity of heterologously expressed Chit42 inBiotechnology reports (Amsterdam, Netherlands) · 2025
    Article
  2. Article
  3. Article
  4. Usage Frequency and Ecotoxicity of Skin Depigmenting Agents.Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Modulation of Plet1 expression by N-Acetylglucosamine through the IL-17 A-MAPK pathway in an imiquimod-induced psoriasis mouse model.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  11. Review
  12. Review
  13. Bacteriophage therapy reducesAntimicrobial agents and chemotherapy · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Life (Basel, Switzerland) · 2023
    Article
  19. Article
  20. An overview of viral chitinases: General properties and biotechnological potential.Experimental biology and medicine (Maywood, N.J.) · 2023
    Review

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jeen-Kuan ChenDepartment of Environment and Biotechnology, Refining & Manufacturing Research Institute, CPC Corporation, 217 Min-Sheng S. Rd, Chiayi, Taiwan.
Chia-Rui Shen
Chao-Lin Liu
Chang Gung University · TWMing Chi University of Technology · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. GlcNAc is the monomeric unit of the polymer chitin, the second most abundant carbohydrate after cellulose. In addition to serving as a component of this homogeneous polysaccharide, GlcNAc is also a basic component of hyaluronic acid and keratin sulfate on the cell surface. In this review, we discuss the industrial production of GlcNAc, using chitin as a substrate, by chemical, enzymatic and biotransformation methods. Also, newly developed methods to obtain GlcNAc using glucose as a substrate in genetically modified microorganisms are introduced. Moreover, GlcNAc has generated interest not only as an underutilized resource but also as a new functional material with high potential in various fields. Here we also take a closer look at the current applications of GlcNAc, and several new and cutting edge approaches in this fascinating area are thoroughly discussed.

Indexed as

AcetylglucosamineChitinChitinasesCosmeticsGlucoseHumansHydrolysisN-Acetylneuraminic AcidPolysaccharidesAcetylglucosamineChitinChitinasesCosmeticsGlucoseN-Acetylneuraminic AcidPolysaccharidescarbohydratechitinN-acetylglucosamine

Identifiers

PMID20948902
PMCPMC2953398
OpenAlexW2013647096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.